Relationship of dietary magnesium intake and serum magnesium with hypertension: a review

Banjanin, Nikolina; Belojević, Goran

doi:10.1684/mrh.2021.0492

Cited by 9 publications

(9 citation statements)

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“…On the other hand, when there are initial disruptions in the balance of magnesium, specifically a decrease in magnesium levels, it leads to a subsequent decrease in potassium levels (16). Moreover, there is a strong association observed between the amounts of magnesium and potassium in tissues outside of the kidneys, specifically in skeletal muscle (14). A lack of magnesium triggers potassium depletion in both animals and humans.…”

Section: Discussionmentioning

confidence: 99%

الدور الواعد لتورات المغنيسيوم في إدارة ارتفاع ضغط الدم

Huda Latif Hasan,

Maysaa Jalal Majeed

2024

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قد يساعد مغنيسيوم تورات الأشخاص المصابين بارتفاع ضغط الدم في خفض ضغط الدم لديهم. تقدم الفوائد المحتملة لمغنيسيوم تورات في علاج ارتفاع ضغط الدم وسهولة استخدام المكملات دعمًا لهذه النظرية. تهدف الدراسة إلى فحص فعالية مغنيسيوم تورات في إدارة ارتفاع ضغط الدم وخفض مستويات ضغط الدم لدى الأفراد الذين يعانون من ارتفاع ضغط الدم المزمن. شملت هذه الدراسة 164 فردًا تتراوح أعمارهم بين (40-70) عامًا. تم تقسيمهم إلى مجموعتين. المجموعة الأولى تحتوي على 82 شخصًا بصحة جيدة، بما في ذلك الأفراد بدون ارتفاع ضغط الدم، والمجموعة الثانية تحتوي على 82 مريضًا بارتفاع ضغط الدم، تم تناول عشرين منهم مغنيسيوم تورات لمدة شهر (30 يومًا). تم تحليل مستويات الكورتيزول والمغنيسيوم والبوتاسيوم في المصل، بالإضافة إلى قياس ضغط الدم الانقباضي والانبساطي لكلا المجموعتين قبل وبعد تناول المكملات الغذائية. النتائج: بعد تعديل العمر بين المجموعتين، أظهرت مستويات الكورتيزول انخفاضًا ملحوظًا في مستوى الكورتيزول في المصل (316.30±59.6 نانومول/ديسيلتر)، وزيادة ملحوظة في مستويات المغنيسيوم في المصل (2.01±0.27 ملغ/ديسيلتر) والبوتاسيوم في المصل (4.31±0.25 ملمول/لتر) بعد تناول مغنيسيوم تورات، مع انخفاض ملحوظ في مستوى ضغط الدم ضغط الدم الانقباضي (130.00±7.20 ملم زئبق) وضغط الدم الانبساطي (80.30±3.64 ملم زئبق). في الختام، يؤدي تكملة مغنيسيوم تورات ليس فقط إلى استعادة الانخفاضات المرتبطة بارتفاع ضغط الدم في مستويات المغنيسيوم والبوتاسيوم في المصل، ولكنها أيضًا تؤدي إلى انخفاض ملحوظ في مستويات الكورتيزول في المصل. تلك التحسينات تدل على فائدة علاجية محتملة في إدارة ارتفاع ضغط الدم، خاصة عندما يتم الجمع بينها وبين انخفاض ملحوظ في ضغط الدم.

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Section: Discussionmentioning

confidence: 99%

الدور الواعد لتورات المغنيسيوم في إدارة ارتفاع ضغط الدم

Huda Latif Hasan,

Maysaa Jalal Majeed

2024

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“…[121] Several studies have shown that Mg has benefits in various aspects of immune, endocrine, and neurological stability of the organism. [122][123][124][125][126][127] Mundaca's team has developed a Zn-based microrocket pill based on the mentioned characteristics. This microrocket pill utilizes an asymmetric tubular design to ensure excellent motility of the microrockets in gastric acid.…”

Section: Water-propelled Micro/nanomotorsmentioning

confidence: 99%

“…[ 121 ] Several studies have shown that Mg has benefits in various aspects of immune, endocrine, and neurological stability of the organism. [ 122–127 ]…”

Section: Design and Application Of Active Carriersmentioning

confidence: 99%

Micro/Nanomotors for Oral Delivery of Drugs: From Design to Application

Xie,

Luo,

Zhang

et al. 2023

Advanced NanoBiomed Research

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Oral administration, as a traditional approach of taking therapeutic drugs, is easily accepted by patients due to its convenience and compliance. However, the harsh digestive environment and mucosa‐epithelial cell barriers limit the absorption of drugs through the oral route, particularly for biomacromolecules such as protein, peptide, or nucleic acid drugs. To address this issue, active carriers such as micro/nanomotors and mechanical devices have been engineered as novel delivery systems that are capable of converting various energy into mechanical force. The active delivery of these carriers holds promise for overcoming absorptive barriers and improving drug delivery efficiency, making them an attractive option for precision medicine applications that include drug delivery, gene and cell therapy, biopsy, tissue penetration, intracellular delivery, and biosensing. This article presents an overview of the progress and challenges associated with orally delivering macromolecular drugs, as well as strategies to enhance drug absorption. Additionally, it discusses recent developments and potential applications of active carriers in drug delivery and related fields, which may provide inspiration for future research.

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“…Magnesium is a natural calcium channel blocker, inhibiting calcium from infiltrating cells [ 24 ]. As the literature states, regulating calcium participation is a key component for maintaining the uterine muscle quiescent all throughout pregnancy [ 25 ].…”

Section: Reviewmentioning

confidence: 99%

“…Magnesium acts as a natural calcium channel blocker, inhibiting calcium influx into smooth muscle cells [ 24 ]. By reducing intracellular calcium concentrations, magnesium helps maintain muscle relaxation and prevent excessive uterine contractions [ 13 ].…”

Section: Reviewmentioning

confidence: 99%

Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review

Deeksha¹,

Pajai²,

Cherukuri³

2023

Cureus

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Preterm labor, regarded as the onset of labor before 37 weeks of gestation, is a highly prevalent issue in obstetrics with repercussions for neonatal health. This review article presents an in-depth analysis of the alliance between serum magnesium levels and preterm labor. The review explores the physiological roles of magnesium right through pregnancy, including its significance for energy metabolism, smooth muscle contraction, deoxyribonucleic acid (DNA), and protein synthesis. It addresses cellular transport and the homeostasis of magnesium. The pathophysiological processes encompassing inflammation, oxidative stress, calcium regulation, smooth muscle contractility, and neuroendocrine pathways are investigated. The review evaluates epidemiological studies investigating the alliance between serum magnesium levels and preterm labor. The review incorporates an assortment of study varieties, such as observational studies, case-control studies, prospective cohort studies, and meta-analyses. In the course of reviewing the prognostic relevance of serum magnesium levels in premature labor, therapeutic implications involving diagnostic precision, prognostic significance, and therapeutic response assessment have additionally been addressed. Therapeutic interventions targeting magnesium levels, such as magnesium supplementation, tocolytic therapy, and the role of magnesium in antenatal corticosteroid administration, are explored. This review provides an indepth evaluation of the correlation between serum magnesium levels and preterm labor, stressing its therapeutic significance and repercussions for future research and treatment strategies.

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Relationship of dietary magnesium intake and serum magnesium with hypertension: a review

Cited by 9 publications

References 0 publications

الدور الواعد لتورات المغنيسيوم في إدارة ارتفاع ضغط الدم

الدور الواعد لتورات المغنيسيوم في إدارة ارتفاع ضغط الدم

Micro/Nanomotors for Oral Delivery of Drugs: From Design to Application

Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor: An Inclusive Review

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