Relationship of Diet, Axial, and Appendicular Bone Mass in Normal Premenopausal Women

Desai, Sanjay S.; Baran, Daniel T.; Grimes, Joyce; Gionet, M.; Milne, Moira

doi:10.1097/00000441-198704000-00003

Cited by 5 publications

(1 citation statement)

References 10 publications

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“…While some studies support the finding that calcium has a positive impact on bone mass, 27,45,46 others have shown no benefit of dietary calcium on bone mass. [47][48][49][50] It is suggested that regions with high trabecular content, such as the spine, appear to be stable after growth and until menopause unless hormonal changes occur, and are less influenced by calcium intake. 51 Many studies have reported a correlation between BMD and weight, height or BMI.…”

Section: Discussionmentioning

confidence: 99%

Familial Resemblance of Bone Mineral Density Between Females 18 Years and Older and Their Mothers

Picard

Imbach

et al. 2001

Can J Public Health

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Section: Discussionmentioning

confidence: 99%

Familial Resemblance of Bone Mineral Density Between Females 18 Years and Older and Their Mothers

Picard

Imbach

et al. 2001

Can J Public Health

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Long-term L-Thyroxine Therapy Is Associated With Decreased Hip Bone Density in Premenopausal Women

Paul

Kerrigan²,

Kelly³

et al. 1988

JAMA

222

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The effect of long-term L-thyroxine (L-T4) therapy on axial skeleton bone density was studied in 31 premenopausal women; the bone densities of these women were compared with the bone densities of 31 age- and weight-matched women without thyroid or bone abnormalities. The women receiving L-T4 therapy had been receiving the medication for a minimum of five years. There was no difference in calcium intake or excretion between the L-T4-treated women and the controls. Women receiving L-T4 had increased serum thyroxine concentrations (134 +/- 5 vs 95 +/- 3 nmol/L [10.4 +/- 0.4 vs 7.4 +/- 0.2 micrograms/dL]), an increased free thyroxine index (9.4 +/- 0.4 vs 6.8 +/- 0.2), and decreased serum thyroid-stimulating hormone concentrations (0.9 +/- 0.2 mU/L vs 2.1 +/- 0.3 mU/L [0.9 +/- 0.2 vs 2.1 +/- 0.3 microU/mL]). Serum triiodothyronine concentrations were normal and were similar in both groups. Women treated with L-T4 had a 12.8% lower bone density at the femoral neck and a 10.1% lower bone density at the femoral trochanter compared with matched controls. In contrast, lumbar spine bone density was similar in the two groups. The data suggest that long-term L-T4 therapy, which is often given at supraphysiologic dosages, may predispose patients to decreased bone density in the hip and may increase the risk of age-related bone loss. It is advisable, therefore, to employ a dosage of L-T4 that is carefully monitored to avoid the long-term use of dosages that are excessive for the thyroid condition being treated.

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Determinants of Maintenance of Bone Mass

Baran

1999

The Aging Skeleton

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Relationship of Diet, Axial, and Appendicular Bone Mass in Normal Premenopausal Women

Cited by 5 publications

References 10 publications

Familial Resemblance of Bone Mineral Density Between Females 18 Years and Older and Their Mothers

Familial Resemblance of Bone Mineral Density Between Females 18 Years and Older and Their Mothers

Long-term L-Thyroxine Therapy Is Associated With Decreased Hip Bone Density in Premenopausal Women

Determinants of Maintenance of Bone Mass

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