Relationship of depression with cognitive insight and socio-occupational outcome in patients with schizophrenia

Grover, Sandeep; Nehra, Ritu; Chakrabarti, Subho

doi:10.1177/0020764017691314

Cited by 12 publications

(6 citation statements)

References 87 publications

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“…Of note, some studies examining the relationship of clinical insight and depression in schizophrenia have failed to find significant relationships between these variables 86 . A metaanalysis of 50 cross-sectional studies found a weak relationship between clinical insight and depression, but reported that longitudinal studies suggested a stronger, more complex relationship which plays out differently depending upon the circumstances of the individual person's life 87 .…”

Section: Good Clinical Insight Is Associated With Depression and Poormentioning

confidence: 99%

“…Greater levels of cognitive insight have also been linked to heightened levels of depression 77,86 , as well as lower levels of self-reported subjective recovery 89 and subjective quality of life 90 . Phelan et al 91 suggested a complex relationship in which higher self-certainty was linked to better interviewer-rated quality of life only when patients had greater levels of psychopathology.…”

Section: Good Cognitive Insight Is Associated With Depression and Poomentioning

confidence: 99%

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Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments

et al. 2018

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Poor insight in schizophrenia is prevalent across cultures and phases of illness. In this review, we examine the recent research on the relationship of insight with behavior, mood and perceived quality of life, on its complex roots, and on the effects of existing and emerging treatments. This research indicates that poor insight predicts poorer treatment adherence and therapeutic alliance, higher symptom severity and more impaired community function, while good insight predicts a higher frequency of depression and demoralization, especially when coupled with stigma and social disadvantage. This research also suggests that poor insight may arise in response to biological, experiential, neuropsychological, social-cognitive, metacognitive and socio-political factors. Studies of the effects of existing and developing treatments indicate that they may influence insight. In the context of earlier research and historical models, these findings support an integrative model of poor insight. This model suggests that insight requires the integration of information about changes in internal states, external circumstances, others' perspectives and life trajectory as well as the multifaceted consequences and causes of each of those changes. One implication is that treatments should, beyond providing education, seek to assist persons with schizophrenia to integrate the broad range of complex and potentially deeply painful experiences which are associated with mental illness into their own personally meaningful, coherent and adaptive picture.

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Section: Good Clinical Insight Is Associated With Depression and Poormentioning

confidence: 99%

Section: Good Cognitive Insight Is Associated With Depression and Poomentioning

confidence: 99%

Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments

et al. 2018

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“…The questionnaire algorithm allows to exclude the diagnosis during the interview and, therefore, depending on the answers obtained, it is not necessary to apply all the questions of the instrument. A study found that the kappa value of the Calgary Depression Scale for Schizophrenia (CDSS) and the of MDE module of the MINI indicated good concurrent validity, and the rates of depression in schizophrenia identified by these two scales were very similar (25% for the MINI and 23.5% for the CDSS, Grover et al, 2017). Also, a study points out that the MINI's reliability was (Henrique et al, 2004).…”

Section: Study Variables and Measuresmentioning

confidence: 99%

Family environment and depressive episode are associated with relapse after first‐episode psychosis

Silva

Freitas

Shuhama

et al. 2021

Psychiatric Ment Health Nurs

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“…These differences in clinical assessment could at least in part account for our contrasting results compared with previous works. We suppose that the avolition dimension of the BNSS, as experiential domain of negative symptoms including avolition, anhedonia, and asociality, similarly to depression in other studies 45,46 , can support a self-evaluation of real-life functioning similar to the one provided by the caregiver. In other words, a higher degree of avolition could enhance a more "objective" perception of patients' limits of functioning.…”

Section: Discussionmentioning

confidence: 82%

Accuracy of self-assessment of real-life functioning in schizophrenia

et al. 2021

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A consensus has not yet been reached regarding the accuracy of people with schizophrenia in self-reporting their real-life functioning. In a large (n = 618) cohort of stable, community-dwelling schizophrenia patients we sought to: (1) examine the concordance of patients’ reports of their real-life functioning with the reports of their key caregiver; (2) identify which patient characteristics are associated to the differences between patients and informants. Patient-caregiver concordance of the ratings in three Specific Level of Functioning Scale (SLOF) domains (interpersonal relationships, everyday life skills, work skills) was evaluated with matched-pair t tests, the Lin’s concordance correlation, Somers’ D, and Bland–Altman plots with limits of agreement (LOA). Predictors of the patient-caregiver differences in SLOF ratings were assessed with a linear regression with multivariable fractional polynomials. Patients’ self-evaluation of functioning was higher than caregivers’ in all the evaluated domains of the SLOF and 17.6% of the patients exceeded the LOA, thus providing a self-evaluation discordant from their key caregivers. The strongest predictors of patient-caregiver discrepancies were caregivers’ ratings in each SLOF domain. In clinically stable outpatients with a moderate degree of functional impairment, self-evaluation with the SLOF scale can become a useful, informative and reliable clinical tool to design a tailored rehabilitation program.

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Relationship of depression with cognitive insight and socio-occupational outcome in patients with schizophrenia

Abstract: Our results suggest that one-fourth of patients with schizophrenia have depression, compared to HDRS and PANSS-D, CDSS has highest concordance with clinician's diagnosis of depression and presence of depression is related to cognitive insight.

Cited by 12 publications

References 87 publications

Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments

Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments

Family environment and depressive episode are associated with relapse after first‐episode psychosis

Accuracy of self-assessment of real-life functioning in schizophrenia

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