Relationship between vitamin A status and anaemia among school age children in Benin

Atimati, AO; Abiodun, PO; Ofovwe, GE

doi:10.4314/njp.v40i4.6

Cited by 4 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of vitamin-A deficiency (VAD) in the current study was lower than reported in a study conducted among children 2 to 10 years old in Eastern Region of Ghana [30]. The prevalence of VAD reported among children in Benin City (29.6 %) [31], was similar to that of the present study. The present finding shows that VAD is still of public health concern among children in the study community as shown by serum retinol concentration cut offs [32].…”

Section: Anaemia and Vitamin-a Statussupporting

confidence: 81%

Anaemia, vitamin-A deficiency, anthropometric nutritional status and associated factors among young school children in Kodzobi, Ghana, a peri-urban community

Tohouenou¹,

Egbi²,

Steiner-Asiedu³

2019

AJFAND

View full text Add to dashboard Cite

Anaemia, vitamin-A deficiency and under nutrition are prevalent among children at levels of public health significance in developing countries of which Ghana is no exception. The objective of this study was to assess the anaemia, low vitamin-A level and anthropometric nutritional status of 162 randomly selected young Ghanaian school children 4-8 years in Kodzobi, a peri-urban community and establish associated factors. Questionnaires were used to collect background data from parents of study participants. Vitamin-A and haemoglobin concentrations were determined using High Performance Liquid Chromatography and Haemocue hemoglobinometer, respectively. Malaria parasitaemia was examined by the Giemsa staining technique. Weight and height measurements were taken according to WHO's standard procedures to assess participants' nutritional status. The mean haemoglobin and serum retinol concentrations were 11.6 ± 1.1 g/dl and 22.8 ± 6.5 µg/dl, respectively. Prevalence of anaemia and vitamin-A deficiency among study participants were 38.3 % and 24.0 %, respectively. The prevalence of underweight, stunting, thinness and overweight were 9.3 %, 9.9 %, 4.3 % and 3.7 %, respectively. Haemoglobin correlated positively and significantly with weight, weight-forage and body mass index-forage z scores. Child's sex, vitamin-A status and parental monthly income associated with anaemia status. Females had a higher risk of being anaemic compared to males (OR = 2.519; 95 % CI: 0.965-6.580; p = 0.049). Participants with normal vitamin-A concentration were at lower risk of being anaemic (OR = 0.302; 95 % CI: 0.109-0.840; p = 0.022) than those with low vitamin-A concentration. Anaemia and young child age negatively associated with vitamin-A status, at p = 0.039 and p = 0.037, respectively. Anaemia and vitamin-A deficiency are issues of public health importance among school-aged children in Ghana. There is, therefore, the need to invest in actions that prevent their occurrence and management especially among children of school going age.

show abstract

Section: Anaemia and Vitamin-a Statussupporting

confidence: 81%

Anaemia, vitamin-A deficiency, anthropometric nutritional status and associated factors among young school children in Kodzobi, Ghana, a peri-urban community

Tohouenou¹,

Egbi²,

Steiner-Asiedu³

2019

AJFAND

View full text Add to dashboard Cite

show abstract

“…in Benin city, Nigeria [43] and 44.0% in Nsukka, Nigeria [44]. The result of this study was also lower than the prevalence of VAD in Uganda (27.9%) and Tanzania (24%) [11].…”

Section: Antioxidant Vitamins Acecontrasting

confidence: 59%

Effects of Antioxidant Vitamins ACE and Iron Supplements on Visual Impairment among Primary and Secondary School Children in Delta State, Nigeria

Moyegbone,

Nwose,

Ofili

et al. 2023

Act Sci Oph

View full text Add to dashboard Cite

The eyes like every other organ of the body, are biochemical elements that respond to both helpful or harmful biochemical stimuli leading to either a healthy or pathological state. Anaemia, antioxidant vitamin deficiencies and visual impairment (VI) are public health problems resulting in poor eye health globally. This study aimed to determine the relationship among anaemia, antioxidant vitamins and VI as well as the effect of antioxidant vitamins and iron supplements on visual acuity and anaemia. A pretest-posttest study of 201 respondents randomly selected from primary and secondary schools in three senatorial districts of Delta State, Nigeria.Sociodemographic data and visual acuity tests were done before and after intervention. Preventive intervention with a single dose of vitamin A, daily Vitamin C, weekly vitamin E, and twice weekly ferrous sulphate supplements was administered for five weeks. Spectacle prescriptions were administered to correct refractive errors (RE). Pretest-posttest haemoglobin and serum vitamins ACE were done using JENWAY 6320D Spectrophotometer. Data were analysed using SPSS version 28.0. Statistical significance was defined as P< 0.05. Findings showed that 83 (41.3%) were males and 118 (58.7%) were females with a mean age of 12.30± 3.14 years. Prevalence of anaemia and VI at baseline was 38.3% and 28.9% respectively, and 0% and 5.5% post-intervention respectively.Prevalence of vitamins A and C at baseline was 12.4% and 12.9% respectively, and post-intervention was 6.0% and 15.9% respectively.Prevalence of vitamin E at baseline and post-intervention was 0.0% respectively. RE was the major cause of VI with a prevalence of 23.4%. The association between visual impairment at baseline and impaired vision with spectacle prescription intervention was statistically significant (P=0.001). The correlation of anaemia, vitamins ACE and VI were not statistically significant (P>0.05). Odd ratios of vitamins ACE and iron supplements were predicted to decrease the risk of having anaemia and VI, though not statistically significant (P>0.05). This study showed that antioxidant vitamins and iron supplementation as well as spectacle prescription were effective in reducing the prevalence of anaemia, antioxidant vitamin deficiencies and visual impairment among primary and secondary school children in Delta State.

show abstract

“…It is hypothesized that VAD causes anemia through 3 mechanisms: modulation of erythropoiesis, reduction of the body’s immunity to infectious diseases thus leading to anemia of infection and modulation of iron metabolism [ 21 , 25 ]. Both observational studies [ 26 – 28 ] and randomized controlled trials [ 29 – 31 ] have reported an association between vitamin A status and iron status. VAD may increase the risk of iron deficient-erythropoiesis and anemia as a result of altering the absorption, storage, release or transport of iron to the marrow [ 32 ].…”

Section: Introductionmentioning

confidence: 99%

Subclinical inflammation influences the association between vitamin A- and iron status among schoolchildren in Ghana

2017

View full text Add to dashboard Cite

Background and objectiveIn resource-poor settings, micronutrient deficiencies such as vitamin A deficiency may co-exist with iron-deficiency. In this study we assessed the iron and vitamin A status of schoolchildren and the association between vitamin A and iron status.MethodsA cross-sectional design using the baseline data of a dietary intervention trial conducted among randomly selected 5–12 years old schoolchildren (n = 224) from 2 rural schools in northern Ghana. Hemoglobin (Hb), serum ferritin (SF) and serum transferrin receptor (sTfR) concentrations were used as measures of iron status. Retinol binding protein (RBP) was used as a measure of vitamin A status. Subclinical inflammation (SCI) was measured using C-reactive protein (CRP) and α1-acid glycoprotein (AGP) concentrations. We examined the cross-sectional association between vitamin A and iron status biomarkers with multiple linear regressions.ResultsThe proportions of schoolchildren with anemia (WHO criteria), iron-deficiency (ID, SF <15μg/l and/or sTfR >8.5mg/l) and iron-deficiency anemia (IDA, concurrent anemia and ID) were 63.8%, 68.3% and 46.4% respectively. Low or marginal vitamin A status (0.70 μmol/l ≤ RBP < 1.05μmol/l) was present in 48.2% while 37.5% of the schoolchildren had vitamin A deficiency (VAD, RBP <0.70 μmol/l). The prevalence of SCI as well as concurrent VAD and ID were 48.7% and 25% respectively. RBP was associated with Hb (β = 7.2, P = 0.05) but not SF (β = 20.7, P = 0.33) and sTfR concentration (β = 12.0, P = 0.63). In the presence of SCI, RBP was not associated with hemoglobin status but a significant positive association was observed among children without SCI.ConclusionsThe study shows that RBP is significantly associated with Hb concentration but not with SF and sTfR. The observed relationship between RBP and Hb is only significant in the absence of SCI.

show abstract

Relationship between vitamin A status and anaemia among school age children in Benin

Cited by 4 publications

References 12 publications

Anaemia, vitamin-A deficiency, anthropometric nutritional status and associated factors among young school children in Kodzobi, Ghana, a peri-urban community

Anaemia, vitamin-A deficiency, anthropometric nutritional status and associated factors among young school children in Kodzobi, Ghana, a peri-urban community

Effects of Antioxidant Vitamins ACE and Iron Supplements on Visual Impairment among Primary and Secondary School Children in Delta State, Nigeria

Subclinical inflammation influences the association between vitamin A- and iron status among schoolchildren in Ghana

Contact Info

Product

Resources

About