Relationship between Virulence Gene Profiles of Atypical Enteropathogenic
            <i>Escherichia coli</i>
            and Shiga Toxin- Producing
            <i>E. coli</i>
            Isolates from Cattle and Sheep in New Zealand

Cao, Mingshu; Bennett, Jenny; Nicol, Carolyn; Thomson-Carter, Fiona M.; Attwood, Graeme T.

doi:10.1128/aem.02528-09

Cited by 13 publications

(10 citation statements)

References 32 publications

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“…The results from the previous studies, where the similarity of the E. coli isolates from humans and animals has been investigated are somewhat ambiguous (Cookson et al. ; Clermont et al. ).…”

Section: Discussionmentioning

confidence: 98%

Prevalence of diarrheagenic Escherichia coli virulence genes in the feces of slaughtered cattle, chickens, and pigs in Burkina Faso

et al. 2012

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We investigated the prevalence of the virulence genes specific for five major pathogroups of diarrheagenic Escherichia coli (DEC) in primary cultures from feces of animals slaughtered for human consumption in Burkina Faso. For the study, 704 feces samples were collected from cattle (n = 304), chickens (n = 350), and pigs (n = 50) during carcass processing. The presence of the virulence-associated genes in the mixed bacterial cultures was assessed using 16-plex polymerase chain reaction (PCR). Virulence genes indicating presence of DEC were detected in 48% of the cattle, 48% of the chicken, and 68% of the pig feces samples. Virulence genes specific for different DECs were detected in the following percentages of the cattle, chicken, and pig feces samples: Shiga toxin-producing E. coli (STEC) in 37%, 6%, and 30%; enteropathogenic E. coli (EPEC) in 8%, 37%, and 32%; enterotoxigenic E. coli (ETEC) in 4%, 5%, and 18%; and enteroaggregative E. coli (EAEC) in 7%, 6%, and 32%. Enteroinvasive E. coli (EIEC) virulence genes were detected in 1% of chicken feces samples only. The study was the first of its kind in Burkina Faso and revealed the common occurrence of the diarrheal virulence genes in feces of food animals. This indicates that food animals are reservoirs of DEC that may contaminate meat because of the defective slaughter and storage conditions and pose a health risk to the consumers in Burkina Faso.

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Section: Discussionmentioning

confidence: 98%

Prevalence of diarrheagenic Escherichia coli virulence genes in the feces of slaughtered cattle, chickens, and pigs in Burkina Faso

et al. 2012

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“…These strains were consequently termed ‘EHEC‐LST’. The closer relatedness of (at least a fair number of) ATEC strains to EHEC rather than to EPEC is further emphasized by studies of strains isolated from cattle and sheep – the common host of EHEC (Cookson et al ., 2010). Loss and gain of genes during E. coli infections is a common event in the human intestine (Mellmann et al ., 2009) and may result in the interconversion of EHEC to apparent ATEC strains.…”

Section: Pathogroup Discrimination and Putative Implications For Diagmentioning

confidence: 99%

LEEways: tales of EPEC, ATEC and EHEC

Schmidt

2010

Cellular Microbiology

144

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SummaryIntestinal pathogenic Escherichia coli are a major cause of worldwide morbidity and mortality. Currently seven intestinal pathovars are recognized causing a wide range of intestinal disorders that are sometimes associated with severe and even lethal complications. The arsenal of virulence factors is used to subvert cellular functions of the host thereby enhancing adaptation, virulence and pathogenicity. Virulence factor profiles are largely the result of the acquisition of mobile genetic elements such as prophages and pathogenicity islands. A group of highly adapted intestinal pathogenic E. coli that are characterized by the induction of 'attaching-and-effacing (A/E) lesions' have acquired a decisive pathogenicity island, the 'locus of enterocyte effacement -LEE' by horizontal gene transfer. This review focuses on recent advances in our understanding of A/E E. coli. It highlights novel functions of effector proteins, addresses the LEE flanking regions where additional genetic elements such as the LifA/Efa1 region have been identified, and points to implications for diagnostics and therapy due to the putative interconversion of A/E E. coli during infection.

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“…До настоящей работы в доступной литературе отсутствовали сообщения о выделении от больных ГК STEC-штаммов, в которых бы одновременно детектировали гены шига-токсина 2с и интимина йота 2. Ранее гены интимина йота 2 обнаруживали только в группе энтеропатогенных штаммов E. coli (EPEC), которые, как известно, не продуцируют шига-токсины [13][14][15].…”

Section: Discussionunclassified

“…Первый характерен для штаммов EHEC, тогда как ген интимина йота 2 не ассоциирован со STEC-штаммами и до сих пор был обнаружен только в энтеропатогенных штаммах E. coli (EPEC), т.е. штаммах, не продуцирующих шига-токсины [13][14][15].…”

Section: дополнительные результаты исследованияunclassified

Molecular-genetic Characterization of Shiga-Toxin Producing Escherichia Coli Isolated During a Food-Borne Outbreak in St. Petersburg in 2013

Онищенко

Dyatlov

Svetoch

et al. 2015

ARAMS

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Relationship between Virulence Gene Profiles of Atypical Enteropathogenic Escherichia coli and Shiga Toxin- Producing E. coli Isolates from Cattle and Sheep in New Zealand

Cited by 13 publications

References 32 publications

Prevalence of diarrheagenic Escherichia coli virulence genes in the feces of slaughtered cattle, chickens, and pigs in Burkina Faso

Prevalence of diarrheagenic Escherichia coli virulence genes in the feces of slaughtered cattle, chickens, and pigs in Burkina Faso

LEEways: tales of EPEC, ATEC and EHEC

Molecular-genetic Characterization of Shiga-Toxin Producing Escherichia Coli Isolated During a Food-Borne Outbreak in St. Petersburg in 2013

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