Relationship between trans-generational effects of tetracycline on Daphnia magna at the physiological and whole organism level

Kim, Ho; Yu, Seung‐Ho; Jeong, Tae-Yong; Kim, Sang Don

doi:10.1016/j.envpol.2014.04.022

Cited by 42 publications

(45 citation statements)

References 42 publications

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“…Again, these differences may be due to the magnitude of the warming imposed (Donelson et al., ). Also for contaminants, there is mixed evidence in invertebrates: some studies showed parental exposure increasing the tolerance of the offspring (e.g., Brausch & Salice, ; Kim et al., ; Reátegui‐Zirena et al., ), while other studies showed the opposite (Pölkki et al., ; Schultz et al., ; Yu et al., ).…”

Section: Discussionmentioning

confidence: 99%

“…Transgenerational effects have been described both in response to warming (e.g., Munday, ; Salinas & Munch, ; Shama et al., ) and to pesticide exposure (e.g., Brausch & Salice, ; Kim, Yu, Jeong, & Kim, ) and raise the concern whether we can reliably predict the biological impact of these stressors based on single‐generation experiments (Kim et al., ; Yu, Zhang, & Yin, ). Indeed, transgenerational effects can make offspring both more (e.g., Pölkki, Kangassalo, & Rantala, ; Schultz et al., ) or less (e.g., Brausch & Salice, ; Kim et al., ; Reátegui‐Zirena et al., ) vulnerable to stressors compared to the parental generation. The emerging view based on recent empirical studies on warming is that transgenerational plasticity may buffer the negative effects of warming on ectotherms (Munday, ; Shama et al., ), yet this may be biased because of methodological weaknesses in the design of the studies (Kielland, Bech, & Einum, ).…”

Section: Introductionmentioning

confidence: 99%

“…Transgenerational effects have been described both in response to warming (e.g., Munday, 2014;Salinas & Munch, 2012; and to pesticide exposure (e.g., Brausch & Salice, 2011;Kim, Yu, Jeong, & Kim, 2014) and raise the concern whether we can reliably predict the biological impact of these stressors based on singlegeneration experiments (Kim et al, 2014;Yu, Zhang, & Yin, 2016).…”

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confidence: 99%

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Transgenerational interactions between pesticide exposure and warming in a vector mosquito

Tran

Janssens

Dinh

et al. 2018

Evolutionary Applications

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While transgenerational plasticity may buffer ectotherms to warming and pesticides separately, it remains unknown how combined exposure to warming and pesticides in the parental generation shapes the vulnerability to these stressors in the offspring. We studied the transgenerational effects of single and combined exposure to warming (4°C increase) and the pesticide chlorpyrifos on life‐history traits of the vector mosquito Culex pipiens. Parental exposure to a single stressor, either warming or the pesticide, had negative effects on the offspring: parental exposure to both warming and the pesticide resulted in an overall lower offspring survival, and a delayed offspring metamorphosis. Parental exposure to a single stressor did, however, not alter the vulnerability of the offspring to the same stressor in terms of survival. Parental pesticide exposure resulted in larger offspring when the offspring experienced the same stressor as the parents. Within both the parental and offspring generations, warming made the pesticide more toxic in terms of survival. Yet, this synergism disappeared in the offspring of parents exposed to both stressors simultaneously because in this condition, the pesticide was already more lethal at the lower temperature. Our results indicate that transgenerational effects will not increase the ability of this vector species to deal with pesticides in a warming world. Bifactorial transgenerational experiments are crucial to understand the combined impact of warming and pesticides across generations, hence to assess the efficacy of vector control in a warming world.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Transgenerational interactions between pesticide exposure and warming in a vector mosquito

Tran

Janssens

Dinh

et al. 2018

Evolutionary Applications

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“…Growth (change in length or mass) and cellular energy allocation data are percentage of change in group means relative to study control. Data extracted from: De Coen and Janssen (blue circles); Kim et al , 2012 (orange circles); Muyssen and Janssen (light gray circles); Rueda‐Jasso et al (yellow circles); Soetaert et al (dark gray circles); Vandenbrouck et al (green circles).…”

Section: Defining Bioenergetics‐aopmentioning

confidence: 99%

Bioenergetics‐adverse outcome pathway: Linking organismal and suborganismal energetic endpoints to adverse outcomes

Goodchild

Simpson

Minghetti

et al. 2018

Enviro Toxic and Chemistry

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Adverse outcome pathways (AOPs) link toxicity across levels of biological organization, and thereby facilitate the development of suborganismal responses predictive of whole‐organism toxicity and provide the mechanistic information necessary for science‐based extrapolation to population‐level effects. Thus far AOPs have characterized various acute and chronic toxicity pathways; however, the potential for AOPs to explicitly characterize indirect, energy‐mediated effects from toxicants has yet to be fully explored. Indeed, although exposure to contaminants can alter an organism's energy budget, energetic endpoints are rarely incorporated into ecological risk assessment because there is not an integrative framework for linking energetic effects to organismal endpoints relevant to risk assessment (e.g., survival, reproduction, growth). In the present analysis, we developed a generalized bioenergetics‐AOP in an effort to make better use of energetic endpoints in risk assessment, specifically exposure scenarios that generate an energetic burden to organisms. To evaluate empirical support for a bioenergetics‐AOP, we analyzed published data for links between energetic endpoints across levels of biological organization. We found correlations between 1) cellular energy allocation and whole‐animal growth, and 2) metabolic rate and scope for growth. Moreover, we reviewed literature linking energy availability to nontraditional toxicological endpoints (e.g., locomotor performance), and found evidence that toxicants impair aerobic performance and activity. We conclude by highlighting current knowledge gaps that should be addressed to develop specific bioenergetics‐AOPs. Environ Toxicol Chem 2019;38:27–45. © 2018 SETAC

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“…Indeed the “Daphnia Multi-generation Assay” is already mentioned in Level 5 of the OECD Conceptual Framework for endocrine disrupters. From the available literature on multi-generational effects of chemical contaminants and other stressors (UV radiation and radioactivity) in D. magna or related species, it was not always possible to evaluate whether concentration effect levels increased, decreased or remained unchanged across generations as it is established by OECD; (Baldwin et al, 2001; Brennan et al, 2006; Campos et al, 2016; Dalla Bona et al, 2015; Dietrich et al, 2010; Faassen et al, 2015; Hammers-Wirtz and Ratte, 2000; Huebner et al, 2009; Jacobasch et al, 2014; Jeong et al, 2015; Kim et al, 2012; Kim et al, 2014; LeBlanc et al, 2013; Li et al, 2016; Li et al, 2014; Massarin et al, 2010; Muyssen and Janssen, 2004; Papchenkova et al, 2009; Parisot et al, 2015; Plaire et al, 2013; Sarapultseva and Dubrova, 2016; Völker et al, 2013; Ward and Robinson, 2005; Yang et al, 2013). About half (13 out of 25) of the above mentioned studies followed OECD TG211 or related protocols, which allowed to compare effect concentration levels across generations and hence demonstrating the potential of this protocol for evaluating toxicity beyond a single generation.…”

Section: Introductionmentioning

confidence: 99%

Validation of a two-generational reproduction test in Daphnia magna: An interlaboratory exercise

Barata

Campos

Rivetti

et al. 2017

Science of The Total Environment

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Effects observed within one generation disregard potential detrimental effects that may appear across generations. Previously we have developed a two generation Daphnia magna reproduction test using the OECD TG 211 protocol with a few amendments, including initiating the second generation with third brood neonates produced from first generation individuals. Here we showed the results of an inter-laboratory calibration exercise among 12 partners that aimed to test the robustness and consistency of a two generation Daphnia magna reproduction test. Pyperonyl butoxide (PBO) was used as a test compound. Following experiments, PBO residues were determined by TQD-LC/MS/MS. Chemical analysis denoted minor deviations of measured PBO concentrations in freshly prepared and old test solutions and between real and nominal concentrations in all labs. Other test conditions (water, food, D. magna clone, type of test vessel) varied across partners as allowed in the OECD test guidelines. Cumulative fecundity and intrinsic population growth rates (r) were used to estimate “No observed effect concentrations “NOEC using the solvent control as the control treatment. EC10 and EC-50 values were obtained regression analyses. Eleven of the twelve labs succeeded in meeting the OECD criteria of producing >60 offspring per female in control treatments during 21 days in each of the two consecutive generations. Analysis of variance partitioning of cumulative fecundity indicated a relatively good performance of most labs with most of the variance accounted for by PBO (56.4%) and PBO by interlaboratory interactions (20.2%), with multigenerational effects within and across PBO concentrations explaining about 6% of the variance. EC50 values for reproduction and population growth rates were on average 16.6 and 20.8% lower among second generation individuals, respectively. In summary these results suggest that the proposed assay is reproducible but cumulative toxicity in the second generation cannot reliably be detected with this assay.

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Relationship between trans-generational effects of tetracycline on Daphnia magna at the physiological and whole organism level

Cited by 42 publications

References 42 publications

Transgenerational interactions between pesticide exposure and warming in a vector mosquito

Transgenerational interactions between pesticide exposure and warming in a vector mosquito

Bioenergetics‐adverse outcome pathway: Linking organismal and suborganismal energetic endpoints to adverse outcomes

Validation of a two-generational reproduction test in Daphnia magna: An interlaboratory exercise

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