Relationship between the AB0 Blood System and Proximal Femoral Fracture Patterns in the Turkish Population

Abstract

Objective. AB0 blood groups have shown to be associated with increased risk of several orthopedic disorders such as Achilles tendon rupture and hip osteoarthritis. The objective of this study was to investigate relationships between the AB0 blood system and hip fracture patterns, duration of hospitalization, and amount of blood transfusion. Methods. Data of 308 patients treated due to hip fractures in our hospital between 2017 and 2019 were evaluated. Epicrisis reports and X-rays of the patients included in this study were retrospectively screened, and hip fractures were classified as intracapsular and extracapsular fractures. Patients were divided into A, B, 0, and AB groups according to blood groups. Results. The mean age of the patients was 75.54±13.5 years. Of all patients, 103 had an intracapsular fracture and 205 had an extracapsular fracture. No statistically significant correlation was found between blood groups and fracture patterns. No statistically significant difference was found between the amounts of transfusion according to the blood groups, and no significant difference between the durations of hospitalizations according to the blood groups. Conclusion. In our study population, we could not find a significant relationship between the AB0 blood system and fracture patterns. We think that these potential relationships could be explained with further comprehensive studies with larger populations.

The correlation between knee osteoarthritis and the ABO blood group system in a Turkish population

“…In England, the blood group distribution of Groups A, B, O, and AB is 45%, 9%, 43% and 3%, respectively [9]. The Italian Blood Donation Association reported that the national distribution of Groups A, B, O, and AB is 32.02%, 14.10%, 50.63% and 3.25%, respectively [10]. Li et al reported the Guangzhou Blood Centre control group to be 27.3% group A, 26.5% group B, 38.4% group O and 7.8% group AB [8].…”

“…Blood group A is common in the Turkish population. According to the data of 5 million people reported by the Turkish Red Crescent, blood group distribution is as follows: A: 42.5%, B:15.8%, O: 32.2%, and AB:7.6% [10]. In a study on 288,469 subjects by Ergün et al, conducted in a similar location to that of the current study, the blood group rates were found to be as follows: A: 44.62%, B: 15.45%, O: 32.24%, and AB: 7.69% [16].…”

“…Kuru et al also examined the relationship between hip fractures and ABO blood groups, and determined a relationship between extracapsular fractures and blood group A. In that study by Kuru et al, not only the relationship between disease and ABO blood groups, but also the relationship between the ABO group system and length of hospital stay and blood transfusion was examined [10]. Unlike other studies in the literature, significant differences were found in the revision arthroplasty group of the two groups that received a lot of attention in the current study (early-onset OA and revision arthroplasty).…”

“…The study of a large patient sample included radiological grading and showed the frequency and severity of primary knee OA in ABO blood groups [9]. However, the frequency of ABO blood groups is known to be affected by many factors, and different frequencies are seen between communities and countries [10]. In knee arthroplasty, two patient groups are of importance: a) OA with onset at a young age and b) revision knee arthroplasty with major complications accompanying the inflammatory process.…”