Relationship between Serum IgE and Airway Responsiveness in Adults with Asthma

Abstract

Several cell types and a wide variety of inflammatory mediators are involved in the chronic airway inflammation that characterizes asthma. The study aims to uncover a link between high serum immunoglobulin E IgE levels and childhood asthma. This cross-sectional study was conducted from March to July 2022 at Khyber Teaching Hospital Peshawar, Pakistan. Asthma patients traveling to the clinic's out-of-the-way chest medication branch were given a clear explanation of the review's goal, its system, and its security measures. This study included 65 patients. This study lists demographic, clinical, and useful characteristics. The research review included 18-60-year-old patients. 40 (66.67%) of our 60 patients were men, and 20 (33.33%) were women. Out of 60 cases, 56.67% had severe asthma. The researchers concluded that the serum levels of immunoglobulin E in asthmatics were much higher than those in normal patients. The severity of the patient's asthma was correlated with an increase in their IgE levels, on average.