Relationship Between Sarcopenia and Type 2 Diabetes Mellitus in Elderly Patients

Sayıner, Zeynel Abidin; Öztürk, Zeynel Abidin

doi:10.25179/tjem.2018-62624

Cited by 1 publication

(1 citation statement)

References 32 publications

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“…Strength declines occur more rapidly, and can decrease at a rate of 3-4% per year in men and 2.5-3% per year in women by age 75 [35]. These declines may be attributed to a multitude of factors including genetic predisposition, hormonal changes, disease, sedentary lifestyle, and poor nutrition with advancing age [6,17,21] and seem to be exacerbated in conditions such as insulin resistance [4,45].…”

Section: Introductionmentioning

confidence: 99%

Associations of muscle lipid content with physical function and resistance training outcomes in older adults: altered responses with metformin

et al. 2021

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Preserving muscle mass and strength is critical for long-term health and longevity. Age-related muscle lipid accumulation has been shown to be detrimental to muscle health. In healthy older individuals, we sought to determine whether muscle lipid content, determined from computed tomography, is associated with selfreported physical function, laboratory-measured performance, and the response to progressive resistance training (PRT), and how metformin may alter these responses (N = 46 placebo, 48 metformin). Using multiple linear regression models adjusted for confounders in a large cohort, we show that intermuscular adipose tissue (IMAT) was not associated with baseline function or response to PRT, contrary to previous reports. On the other hand, thigh muscle density (TMD), as an indicator of intra-and extramyocellular lipid (IMCL and EMCL),

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