Relationship between Proliferation of Ehrlich Ascitic Tumor Cells and Status of the Chalone System under Conditions of Modified Photoregimen

Mashanova, O. G.; Romanov, Yu. A.; Antohin, A. I.; Evstaf'ev, V. V.; Filippovich, S. S.

doi:10.1007/s10517-010-1042-9

Cited by 1 publication

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“…Ehrlich tumors are used largely in experimental cancer treatment, prevention, and modeling studies because tumor ocurrence rates after transplantation is very high and tumor growth is extremely rapid. On the other hand, a number of studies related to prevention of Ehrlich tumor (either ascites or solid subtypes) are few (Mashanova et al, 2010;Jukanti et al, 2011;Niang et al, 2011;Salem et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Cancer Preventive Effects of Whole Cell Type Immunization against Mice Ehrlich Tumors

Ayşan

Bayrak²,

Aydemir³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Background: Effects of whole cell type immunization on mice Ehrlich tumours were evaluated. Materials and Methods: After preliminary study, mice were divided two major groups; 1x1000 and 100x1000 live Ehrlich cell transferred major groups, each divided into four subgroups (n: 10). Study groups were immunized with Ehrlich cell lysates in 0, 3, 7, 14 th days and after 30 days of last immunization, live Ehrlich cells were transferred. Mice were observed for six months and evaluated for total and cancer free days. Results: Out of 100x1000 cell transferred solid type study group, all study group mean and tumour free periods were statistically longer than control groups. All 1x1000 Ehrlich cell transferred study groups survived significantly longer than 100x1000 Ehrlich cell transferred groups. Conclusions: Ehrlich mice tumours were prevented and survival prolonged with whole cell type immunization. Effects are related to the number of transferred tumor cells.

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Section: Discussionmentioning

confidence: 99%