2020
DOI: 10.1080/14767058.2020.1771692
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Relationship between pregnancy and coronavirus: what we know

Abstract: The identification in China in December 2019 of a new coronavirus (SARS-CoV-2) immediately rekindled the spotlight on a problem also addressed in the past during the epidemics of SARS in 2002-2003 and MERS in 2012 the implications of a possible infection during pregnancy, both for pregnant women and for fetuses and infants. Pregnancy is characterized by some changes involving both the immune system and the pulmonary physiology, exposing the pregnant woman to a greater susceptibility to viral infections and mo… Show more

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Cited by 30 publications
(29 citation statements)
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References 57 publications
(77 reference statements)
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“…These data not just confronted with initial papers suggesting that pregnant women have a similar or lower risk for COVID-19 severity than the general population, but also doubles the hospitalization rate (15.8 À 21.9%) and ICU admission percentage (1.3 À 2.2%) reported for female patients in the same age range in Spain [12]. Therefore, obstetric patients could be considered as a risk group for COVID-19 severity, as expected, due to their susceptibility to viral infections and pneumonia development, although the ICU admission and mortality rates seem to be lower than SARS-CoV and MERS-CoV epidemics [13].…”
Section: Discussionmentioning
confidence: 86%
“…These data not just confronted with initial papers suggesting that pregnant women have a similar or lower risk for COVID-19 severity than the general population, but also doubles the hospitalization rate (15.8 À 21.9%) and ICU admission percentage (1.3 À 2.2%) reported for female patients in the same age range in Spain [12]. Therefore, obstetric patients could be considered as a risk group for COVID-19 severity, as expected, due to their susceptibility to viral infections and pneumonia development, although the ICU admission and mortality rates seem to be lower than SARS-CoV and MERS-CoV epidemics [13].…”
Section: Discussionmentioning
confidence: 86%
“…In previous studies on SARS and MERS, complications such as abortion and miscarriage have been observed in infected pregnant women [29]. In another study on pregnancy evaluating the effect of other coronaviruses known to infect humans, the vertical transmission of SARS CoV could not be demonstrated and findings of thrombotic vasculopathy resulting in decreased fetal perfusion were detected in placental studies on this virus [60]. Severe complications such as perinatal death, premature birth, intrauterine growth retardation in pregnant women infected with SARS CoV have been observed in previous studies, and SARS CoV-2 infection may have similar perinatal outcomes [58].…”
Section: Discussionmentioning
confidence: 99%
“…Fever, the most common symptom in pregnant women with COVID-19, can damage the fetal neurons and lead to negative neurodevelopmental outcomes. Therefore, long-term follow-up may be required for the babies of women with COVID-19 during their pregnancy [60].…”
Section: Discussionmentioning
confidence: 99%
“…Not only IFN-γ and IL-1, but also IL-4 and IL-10 are also present in the blood. 37 In the pregnant population, the pregnancy itself does not appear to be an aggravating factor and may also be related to the unique immune status during pregnancy.…”
Section: Maternal-fe Tal Immunit Y and Covid -19 Infec Ti Onmentioning
confidence: 99%