1986
DOI: 10.1038/bjc.1986.4
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Relationship between ploidy and steroid hormone receptors in primary invasive breast cancer

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Cited by 68 publications
(29 citation statements)
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References 18 publications
(22 reference statements)
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“…Clinical stage (UICC) was also positively correlated with aneuploidy incidence in their study, but in our series of patients no statistically significant trend was found. Several authors (3,17,20,24) have reported a n inverse correlation between ER status and ploidy where others have not found such a relationship (6,10,16,25). In the present study a simificant correlation was found only with more recently determined ER values after increasing the sensitivity of the assay.…”
Section: Discussionsupporting
confidence: 36%
“…Clinical stage (UICC) was also positively correlated with aneuploidy incidence in their study, but in our series of patients no statistically significant trend was found. Several authors (3,17,20,24) have reported a n inverse correlation between ER status and ploidy where others have not found such a relationship (6,10,16,25). In the present study a simificant correlation was found only with more recently determined ER values after increasing the sensitivity of the assay.…”
Section: Discussionsupporting
confidence: 36%
“…The breast tumor tissue samples were graded according to the Elston and Ellis modification of the Bloom and Richardson grading system (13). Steroid receptor status was routinely assessed using the radioligand binding assay (14). Clinical and pathological data for the cohort is summarized in Table 1.…”
Section: Methodsmentioning
confidence: 99%
“…There is a consistent trend for a greater proportion of diploid tumours to be oestrogen receptor positive when compared to aneuploid tumours; this difference achieves statistical significance in some studies (Bichel et al, 1982;Cornelisse et al, 1984;Coulson et al, 1984;Horsfall et al, 1986) but not in others (Olszewski et al, 1981a;Raber et al, 1982;Taylor et al, 1983;Hedley et al, 1984;McDivitt et al, 1985;Kute et al, 1985).…”
mentioning
confidence: 99%
“…Two thirds (range 54-92%) of human mammary tumours have been reported to be aneuploid (Olszewski et al, 1981a;Raber et al, 1982;Cornelisse et al, 1984;Ewers et al, 1984;Moran et al, 1984;Hedley et al, 1984Hedley et al, , 1985McDivitt et al, 1986;Thorud et al, 1986;Horsfall et al, 1986).…”
mentioning
confidence: 99%