Relationship between Passive and Active Pulsations of Rat Artery as Vascular Extension of Frank—Starling Law

Chronic Effects of Modeled Myocardial Infarction, Thoracic Trauma, and Denervation of Hind Limb on Rheographic Parameters of Rat Femoral Arteries In Situ

“…Exclusively high swing range of passive pulsatile oscillations in the arteries of denervated animals can be an important cue in understanding the peculiar features in the state of blood vessels during neurogenic pathologies and the organismal response to neurotropic influences. Previously, a positive correlation between ΔZ p and ΔZ a in femoral arteries of healthy rats was established [10]. Here, it was expected that the changes in ΔZ p would be accompanied with the parallel ones of ΔZ a .…”

“…In situ recording of RP of a segment of femoral artery with the length of about 4 mm was described elsewhere [8][9][10]. The data were analyzed in the segments of electroimpedance records corresponding to the stable fragments of BP and pneumotachogram traces.…”

“…The passive or active pulsatile modes of artery was established by applying alternating (100 kHz) probe current with the amplitude of 0.2 or 2 mA, respectively [8]. In each of these modes, the maximal and minimal electroimpedance values were measured in a cardiac cycle during the expiration phase, thereupon the swing ranges of pulsatile oscillations ΔZ p and ΔZ a were calculated as the difference between the corresponding maximal and minimal values [10].…”

“…reflecting parallel elevation/decrease of BP and corresponding constriction/dilation of the artery during a cardiocycle, generation of arterial action potentials, and augmented peak-to-peak magnitude (the swing range) of electroimpedance oscillations by an order of magnitude [8][9][10]. A strong positive correlation between the swing ranges of passive (ΔZ p ) and active (ΔZ a ) pulsatile oscillations of arterial electroimpedance made it possible to extend the Frank-Starling law of the heart onto the arteries and to consider this extension as reflection of evolution-consolidated feature in the work of the cardiovascular system [10].…”

“…reflecting parallel elevation/decrease of BP and corresponding constriction/dilation of the artery during a cardiocycle, generation of arterial action potentials, and augmented peak-to-peak magnitude (the swing range) of electroimpedance oscillations by an order of magnitude [8][9][10]. A strong positive correlation between the swing ranges of passive (ΔZ p ) and active (ΔZ a ) pulsatile oscillations of arterial electroimpedance made it possible to extend the Frank-Starling law of the heart onto the arteries and to consider this extension as reflection of evolution-consolidated feature in the work of the cardiovascular system [10]. Since active pulsing of arteries is a diagnostic sign of healthy Previous studies revealed an unknown property of major arteries to pulse in active mode, which differs from the passive one by synphase changes in BP and the current value of arterial electroimpedance vessels [6,7], while pronounced changes in the swing range of pulsatile oscillations were observed in some pathologies [2,13], it seems important to assess the effects of diverse factors on rheographic parameters (RP) of the arteries such as mean electroimpedance Z as well as ΔZ p and ΔZ a .…”