Relationship between parathyroid hormone and impaired microcirculation in moderate essential hypertension

Extensive Necrotizing Livedo reticularis in a Patient with Chronic Renal Failure, Hyperparathyroidism and Coagulation Disorder: Regression After Subtotal Parathyroidectomy

“…Besides these coagulation disorders, oth er mechanisms are of interest; direct involve ment of raised levels of the parathormone in vascular abnormalities with decreasing ve locity of the red blood cells, decreasing diameter and number of cutaneous capillar ies [31], and enhancement of intravascular coagulation by direct interaction with the en dothelium resulting in spontaneous platelet aggregation [5]. These direct effects of para Necrotizing Livedo in Chronic Renal Failure Dermatology 1996;192:167-170 thormone on vessels may be involved in the pathomechanisms of very infrequent reports of necrotizing livedo reticularis occurring in primary hyperparathyroidism 132] and linked with a shift of the intracellular calcium pool in endothelial cells [33].…”