Relationship Between Noninvasive Assessment of Lung Fluid Volume and Invasively Measured Cardiac Hemodynamics

Uriel, Nir; Sayer, Gabriel; Imamura, Teruhiko; Rodgers, D.; Kim, Gene; Raikhelkar, J.; Sarswat, Nitasha; Kalantari, S.; Chung, B.; Nguyen, A.; Burkhoff, Daniel; Abbo, Aharon

doi:10.1161/jaha.118.009175

Cited by 57 publications

(60 citation statements)

References 33 publications

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“…We recently showed that the ReDS measurement correlated with the actual PCWP measured by RHC ( Fig. 2B ) ( 11 ). Given the high sensitivity and moderate specificity, we suggest using ReDS technology to screen for pulmonary congestion in the ambulatory setting.…”

Section: Introductionsupporting

confidence: 52%

Advances in Hemodynamic Monitoring in Heart Failure Patients

Imamura

Narang

2021

Intern. Med.

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Abnormal hemodynamics are associated with poor clinical outcomes in patients with heart failure. Given the invasiveness and unfeasibility of routine right heart catheterization, non-invasive methodologies to monitor hemodynamics are needed. The CardioMEMS™ device is a recently developed technology that enables remote monitoring of pulmonary artery pressures via an implanted sensor located in the distal left pulmonary artery. Along with the CardioMEMS™, a remote dielectric system might be another promising device that reports indirect intra-thoracic filling pressures associated with pulmonary congestion. In patients with advanced heart failure who require left ventricular assist devices, non-invasive hemodynamic monitoring is particularly necessary, given the increased procedural risks of invasive assessments. The HeartWare ventricular assist device flow waveform is a variable under active investigation that might also provide an estimation of filling pressures. This methodology is expected to lead to the development of a smart pump that can adjust its own settings, including the pump speed, automatically by monitoring the hemodynamics.

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Section: Introductionsupporting

confidence: 52%

Advances in Hemodynamic Monitoring in Heart Failure Patients

Imamura

Narang

2021

Intern. Med.

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“…Normal lung measures 20–35% lung fluid content (default target range). The measurement can be done without any skin contact in up to 45 s. Uriel et al 53 . showed using ReDS™ strong correlations in both tissue‐measured fluid content and haemodynamic measurements with pulmonary artery wedge pressure.…”

Section: Novel and Upcoming Devices And Technologiesmentioning

confidence: 99%

A current and future outlook on upcoming technologies in remote monitoring of patients with heart failure

Bekfani

Fudim

Cleland

et al. 2020

European J of Heart Fail

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Heart failure is a major health and economic challenge in both developing and developed countries. Despite advances in pharmacological and device therapies for patients with a reduced left ventricular ejection fraction (LVEF) and heart failure, their quality of life and exercise capacity are often persistently impaired, morbidity and mortality remain high and the health economic and societal costs are considerable. For patients with heart failure and preserved LVEF, diuretic management has an essential role for controlling congestion and symptoms, even if no intervention has convincingly shown to reduce morbidity or mortality. Remote monitoring might improve care delivery and clinical outcomes for patients regardless of LVEF. A great variety of innovative remote monitoring technologies and algorithms are being introduced, including patient self‐managed testing, wearable devices, technologies either integrated into established clinically indicated therapeutic devices, such as pacemakers and defibrillators, or as stand‐alone are in development providing the promise of further improvements in service delivery and clinical outcomes. In this article, we will discuss unmet needs in the management of patients with heart failure, how remote monitoring might contribute to future solutions, and provide an overview of current and novel remote monitoring technologies.

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“…Radar-based sensors (utilizing low-power radio frequency wavelength) are embedded in a system which is used for heart failure management by measuring lung fluid content (ReDS Heart Failure monitor™, Sensible Medical, Netanya, Israel). [25][26][27] The system measures the dielectric properties of tissues. Low-power electromagnetic signals are emitted through the right mid-thorax, and the signals received after passing through the tissue reflect their combined dielectric properties.…”

Section: Vital Signs and Covid-19-focused Sensorsmentioning

confidence: 99%

Technological Developments and Strategic Management for Overcoming the COVID-19 Challenge within the Hospital Setting in Israel

Abbo¹,

Miller²,

Gazit³

et al. 2020

Rambam Maimonides Med J

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The coronavirus disease 2019 (COVID-19) pandemic has remarkably challenged health care organizations and societies. A key strategy for confronting the disease implications on individuals and communities was based on harnessing multidisciplinary efforts to develop technologies for mitigating the disease spread and its deleterious clinical implications. One of the main challenging characteristics of COVID-19 is the provision of medical care to patients with a highly infective disease mandating the use of isolation measures. Such care is complicated by the need for complex critical care, dynamic treatment guidelines, and a vague Technologies for COVID-19 Challenge Rambam Maimonides Medical Journal 2 July 2020  Volume 11  Issue 3  e0026 knowledge regarding the disease's pathophysiology. A second key component of this challenge was the overwhelming surge in patient burden and the relative lack of trained staff and medical equipment which required rapid reorganization of large systems and augmenting health care efficiencies to unprecedented levels. In contrast to the risk management strategies employed to mitigate other serious threats and the billions of dollars that are invested in reducing these risks annually by governments around the world, no such preparation has been shown to be of effect during the current COVID-19 pandemic. Unmet needs were identified within the newly opened COVID-19 departments together with the urgent need for reliable information for effective decision-making at the state level. This review article describes the early research and development response in Israel under the scope of in-hospital patient care, such as non-contact sensing of patients' vital signs, and how it could potentially be weaved into a practical big picture at the hospital or national level using a strategic management system. At this stage, some of the described technologies are still in developmental or clinical evidence generation phases with respect to COVID-19 settings. While waiting for future publications describing the results of the ongoing evidence generation efforts, one should be aware of this trend as these emerging tools have the potential to further benefit patients as well as caregivers and health care systems beyond the scope of the current pandemic as well as confronting future surges in the number of cases.

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Relationship Between Noninvasive Assessment of Lung Fluid Volume and Invasively Measured Cardiac Hemodynamics

Cited by 57 publications

References 33 publications

Advances in Hemodynamic Monitoring in Heart Failure Patients

Advances in Hemodynamic Monitoring in Heart Failure Patients

A current and future outlook on upcoming technologies in remote monitoring of patients with heart failure

Technological Developments and Strategic Management for Overcoming the COVID-19 Challenge within the Hospital Setting in Israel

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