Relationship between neutrophil-to-lymphocyte ratio, d-dimer and troponin-I values and pulmonary embolism severity index

Güzel, Murat; Özgen, Emre; Terzi, Özlem; Demır, Mehmet; Yucel, Murat; Baydın, Ahmet

doi:10.5455/annalsmedres.2019.01.025

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In some previous studies, the ratios of neutrophils/lymphocytes (NLR), monocytes/lymphocytes (MLR), and platelets/lymphocytes (PLR) were shown to be indicative of systemic infl ammation, to play an important role in venous thromboembolism, and to be effective in determining the tendency to thrombosis (9)(10)(11). NLR and PLR were reported to be better indicators of infl ammation than leukocyte counts in the whole blood counts (12), and NLR was shown to be an indicator of prognosis in cancer, cardiac diseases, pulmonary embolism, and sepsis (13)(14)(15)(16)(17)(18)(19)(20)(21). As far as we know, there was no study that investigated the relationship between NLR, MLR, PLR and clinical outcomes in patients with AIS undergoing a mechanical thrombectomy.…”

Section: Aim and Introductionmentioning

confidence: 99%

The relationship between neutrophil/lymphocyte, monocyte/ /lymphocyte, platelet/lymphocyte ratios and clinical outcomes after ninety days in patients who were diagnosed as having acute ischemic stroke in the emergency room and underwent a mechanical thro

Özgen¹,

Güzel²,

Akpinar³

et al. 2020

BLL

View full text Add to dashboard Cite

AIM: To determine whether there was a relationship between the neutrophil/lymphocyte (NLR), monocyte/ /lymphocyte (MLR), and the platelet/lymphocyte ratios (PLR) measured in blood samples taken at admission and clinical outcomes (CO) on the 90th day in patients, who were diagnosed as acute ischemic stroke (AIS) in the emergency department (ED) and underwent a mechanical thrombectomy (MT). METHOD: Patients aged ≥ 18 years, who were diagnosed as AIS in the ED and underwent MT were included in the study. Patients, who received diagnostic codes of "Cerebrovascular Diseases" (CVD) according to the ICD-10 diagnostic codes were identifi ed. One hundred fi fty patients were enrolled in the study. Modifi ed Rankin Scale (mRS) score was used to determine neurologic status on the 90th day. The patients were divided into the two groups: good and poor CO (mRS 0-2 and mRS 3-6, respectively). The groups were compared in terms of age, sex, and NIHSS, ASPECT, and mRS scores. RESULTS: The rates of successful recanalization and good CO were 81.3 % and 38.7 %, respectively. The mortality rate was 22 %. The recanalization rates in the good and poor CO groups were 100 % and 69.6 %, respectively. Recanalization was achieved in 73.6 % of those with hyperlipidaemia and 88.5 % of those without hyperlipidaemia, which was statistically signifi cant (p = 0.034). We observed a statistically signifi cant relationship between the clinical outcome and NLR, MLR, PLR (p < 0.05). As the result of multivariate analysis, we found only NLR as an independent risk factor for poor CO (p = 0.043). There was also a statistically signifi cant difference between mortality and NLR, PLR (p = 0.001). CONCLUSION: We found that NLR, MLR, PLR values were associated with CO after 90 days; high rates were associated with poor CO and low rates were associated with good CO (Tab. 7, Ref. 38).

show abstract