Relationship between mental health and climacteric adjustment in middle aged women: a confirmatory analysis

Khakkar, Maedeh; Kazemi, Ashraf

doi:10.1186/s12905-023-02397-x

Cited by 2 publications

(2 citation statements)

References 27 publications

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“…This was surprising, as older age of menopause onset means longer exposure to endogenous estrogens, which was associated with a lower risk of depression later in life 27 . A recent cross-sectional study showed that middle-aged women with decreased climacteric adjustment, or social-emotional adjustment to perimenopause/menopause, had increased psychological symptoms 28 . One possible explanation for our finding is that women who have passed the transitional phase of the perimenopause have readjusted, hence perceiving less psychological distress a few years after menopause.…”

Section: Discussionmentioning

confidence: 99%

Associations of anti-Müllerian hormone levels among women in their mid-30s with menopausal symptoms ~14 years later

Mahabamunuge,

Wang,

Rifas-Shiman

et al. 2024

Menopause

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Objective The aim of this study was to examine associations of anti-Müllerian hormone (AMH) levels in gravid women in their mid-30s with menopausal symptoms ~14 years later and age at natural menopause. Methods In this prospective analysis, 474 participants in Project Viva, a longitudinal cohort, were enrolled during pregnancy between 1999 and 2002. AMH levels were determined using plasma samples collected 3 years postpartum. Participants completed the Menopause Rating Scale (MRS) and self-reported age at and reason for menopause at the 17 years postpartum visit (Mid-Life Visit). Primary outcomes were individual MRS item responses and total MRS score. To examine associations between AMH levels and menopausal outcomes, we performed linear and logistic regressions, and survival analyses, adjusting for confounding variables. Results Mean (SD) AMH level was 2.80 (2.74) ng/mL, measured at 38.2 (3.9) years. At the Mid-Life Visit, mean (SD) age was 52.3 (3.9) years and total MRS score was 8.0 (5.7). During follow-up, 50% had experienced natural menopause, and self-reported mean (SD) age at natural menopause was 50.4 (3.6) years. AMH in the lowest tertile (mean [SD]: 0.47 [0.32] ng/mL) was associated with higher odds of moderate to severe vaginal dryness (adjusted odds ratio: 2.58; 95% CI: 1.16 to 5.73), a lower MRS psychological subscale (adjusted β: −0.71; 95% CI: −1.35 to −0.07), and earlier attainment of natural menopause (adjusted hazards ratio: 7.1; 95% CI: 4.6 to 11.0) compared with AMH in the highest tertile (mean [SD]: 6.01 [2.37] ng/mL). Conclusions Lower AMH in the mid-30s was associated with earlier menopause and increased odds of vaginal dryness but fewer psychological symptoms ~14 years later.

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Section: Discussionmentioning

confidence: 99%

Associations of anti-Müllerian hormone levels among women in their mid-30s with menopausal symptoms ~14 years later

Mahabamunuge,

Wang,

Rifas-Shiman

et al. 2024

Menopause

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“…Anxiety, depression, and impairment in social functioning may result because of climacteric maladjustment. [ 35 ]…”

Section: Effects Of Menopause On Quality Of Lifementioning

confidence: 99%

Mental health and well-being of women (menarche, perinatal, and menopause)

Kedare,

Kadiani,

Patkar

et al. 2024

Indian Journal of Psychiatry

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Mental well-being is now an increasingly researched and discussed topic that primarily involves taking care of mental health in a preventive manner and is more of a subjective concept. Mental well-being ensures mental health and measures taken toward it can protect the person's overall health. Discussing and researching this concept is of paramount importance as this will not just safeguard an individual life but the society at large. The lifetime of a woman is multidimensionally unique with a complex interplay of biological, sociocultural, and environmental aspects. This demands a diverse variety of factors required to ensure mental well-being in a woman. In addition to this, these determinants vary on the life stage the woman is in. Factors that influence this well-being are also specific when it comes to an Indian context. This chapter considers and discusses in detail the various aspects of the mental health and well-being of women in the pubertal, perinatal, and menopausal age groups. Determinants are unique to particular age groups of women, and measures to focus on and ensure it will be elaborated on. Finally, recommendations towards policy making are also suggested.

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Relationship between mental health and climacteric adjustment in middle aged women: a confirmatory analysis

Cited by 2 publications

References 27 publications

Associations of anti-Müllerian hormone levels among women in their mid-30s with menopausal symptoms ~14 years later

Associations of anti-Müllerian hormone levels among women in their mid-30s with menopausal symptoms ~14 years later

Mental health and well-being of women (menarche, perinatal, and menopause)

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