Relationship between IOP and biomechanical corneal values obtained by ORA

Fuente, C López De La; Sánchez‐Cano, Ana; Pinilla, Isabel; Broto, Lorena Fuentes; Clavo, F Segura

doi:10.1111/j.1755-3768.2012.f004.x

Cited by 2 publications

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“…In this study, we observed that CH increased with the decrease of IOPcc in the pregnant subjects, which also supported a negative correlation between IOPcc and CH ( r = −0.482) from a previous report. 26 A positive correlation between CCT and CH found in our study has also been consistently described in previous publications. 24,27 Nevertheless, we found that CH in the second and the third trimester is significantly higher than that of non-pregnant group after adjustment for IOPcc, indicating the changes in CH in the advancing stages of pregnancy are independent of IOPcc.…”

Section: Discussionsupporting

confidence: 92%

Changes in corneal biomechanics during pregnancy in Chinese healthy female

Yang

et al. 2020

European Journal of Ophthalmology

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Purpose: To evaluate the changes of corneal biomechanics and the intraocular pressure during pregnancy in a Chinese healthy female population. Methods: A total of 222 unrelated Chinese females were recruited: 52 non-pregnant, 15 pregnant in the first trimester, 68 pregnant in the second trimester, and 87 pregnant in the third trimester. The intraocular pressure and corneal biomechanical parameters, including corneal-compensated intraocular pressure, Goldmann-correlated intraocular pressure, corneal hysteresis, and corneal resistance factor, were measured by an Ocular Response Analyzer G3. Central corneal thickness was measured by Lenstar (LS900). Results: Corneal hysteresis and corneal resistance factor were significantly higher in pregnant women at the second and third trimesters. Corneal-compensated intraocular pressure was lower in women at the third trimester of pregnancy ( p = 0.023), but the difference became insignificant after adjustment for corneal hysteresis. Central corneal thickness was marginally higher in pregnant women than non-pregnant women ( p = 0.032). There was a negative correlation between corneal-compensated intraocular pressure and corneal hysteresis ( r = −0.337, p < 0.001) and a positive correlation between central corneal thickness and corneal hysteresis ( r = 0.711, p < 0.0001). After adjustment for corneal-compensated intraocular pressure, corneal hysteresis remained significantly higher in the second and third trimesters of pregnant women than non-pregnant women ( p = 0.031, p = 0.005). Conclusion: This study revealed a significant increase in corneal hysteresis and corneal resistance factor in the second and third trimesters. The increase of corneal hysteresis was independent of corneal-compensated intraocular pressure, indicating pregnant females have unique characteristics in corneal-compensated intraocular pressure and corneal biomechanical properties that may be related to glaucoma and corneal ectatic diseases in pregnancy.

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Section: Discussionsupporting

confidence: 92%

Changes in corneal biomechanics during pregnancy in Chinese healthy female

Yang

et al. 2020

European Journal of Ophthalmology

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“…Correlation of these parameters relative to biometric measurement and IOP remains the subject of studies. According to Lopez de la Fuente et al [20], there is an average negative correlation between IOPcc and CH measured in the patient (r = -0.482). That conclusion was confirmed by studies [9,10], where higher CH values were obtained for lower IOPcc measurements.…”

Section: Biomechanical Parameters Of the Cornea: Ch And Crfmentioning

confidence: 93%

Changes in the parameters of the anterior segment of the eye in pregnant women — literature review

et al. 2018

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The physiology of pregnancy is a curious issue for specialists from different branches of medicine and science. In this systematic review, the attention was focused on changes in eyes during pregnancy and confinement. To summarise and systematize actual knowledge in eyes' changes during pregnancy, publications from years 2011-2017 were analysed. Stud-ies about parameters of corneal endothelial cells, corneal biomechanical parameters, keratometric variables, intraocular pressure and biometry of the anterior chamber were compared. The conducted studies demonstrated the unambiguous character of changes only in case of intraocular pressure, which decreased during the II and III trimesters of pregnancy. Inconsistent study methods and low number of examined patients did not enable to draw explicit conclusions in context of other parameters of the anterior segment of the eye in pregnant women. It is indicated to perform further studies on a representative and homogeneous group of female patients.

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Relationship between IOP and biomechanical corneal values obtained by ORA

Cited by 2 publications

References 0 publications

Changes in corneal biomechanics during pregnancy in Chinese healthy female

Changes in corneal biomechanics during pregnancy in Chinese healthy female

Changes in the parameters of the anterior segment of the eye in pregnant women — literature review

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