“…Second, the relatively low response rate (54.8%) may have resulted in a biased sample and become potential threats to the generalizability of the findings to the whole population. This response rate, however, is comparable to or even higher than that of many mailing or telephone surveys in other countries [12], [16], [29], [30]. Third, although the measure of each construct was carefully developed, the unknown validity and reliability of the study instruments may be of concern, and could result in the difficulties in making cross-population comparisons.…”
BackgroundOverall pandemic A (H1N1) influenza vaccination rates remain low across all nations, including Japan. To increase the rates, it is important to understand the motives and barriers for the acceptance of the vaccine. We conducted this study to determine potential predictors of the uptake of A (H1N1) influenza vaccine in a cohort of Japanese general population.Methodology/Principal FindingsBy using self-administered questionnaires, this population-based longitudinal study was conducted from October 2009 to April 2010 among 428 adults aged 18–65 years randomly selected from each household residing in four wards and one city in Tokyo. Multiple logistic regression analyses were performed. Of total, 38.1% of participants received seasonal influenza vaccine during the preceding season, 57.0% had willingness to accept A (H1N1) influenza vaccine at baseline, and 12.1% had received A (H1N1) influenza vaccine by the time of follow-up. After adjustment for potential confounding variables, people who had been vaccinated were significantly more likely to be living with an underlying disease (p = 0.001), to perceive high susceptibility to influenza (p = 0.03), to have willingness to pay even if the vaccine costs ≥ US$44 (p = 0.04), to have received seasonal influenza vaccine during the preceding season (p<0.001), and to have willingness to accept A (H1N1) influenza vaccine at baseline (p<0.001) compared to those who had not been vaccinated.Conclusions/SignificanceWhile studies have reported high rates of willingness to receive A (H1N1) influenza vaccine, these rates may not transpire in the actual practices. The uptake of the vaccine may be determined by several potential factors such as perceived susceptibility to influenza and sensitivity to vaccination cost in general population.
“…Second, the relatively low response rate (54.8%) may have resulted in a biased sample and become potential threats to the generalizability of the findings to the whole population. This response rate, however, is comparable to or even higher than that of many mailing or telephone surveys in other countries [12], [16], [29], [30]. Third, although the measure of each construct was carefully developed, the unknown validity and reliability of the study instruments may be of concern, and could result in the difficulties in making cross-population comparisons.…”
BackgroundOverall pandemic A (H1N1) influenza vaccination rates remain low across all nations, including Japan. To increase the rates, it is important to understand the motives and barriers for the acceptance of the vaccine. We conducted this study to determine potential predictors of the uptake of A (H1N1) influenza vaccine in a cohort of Japanese general population.Methodology/Principal FindingsBy using self-administered questionnaires, this population-based longitudinal study was conducted from October 2009 to April 2010 among 428 adults aged 18–65 years randomly selected from each household residing in four wards and one city in Tokyo. Multiple logistic regression analyses were performed. Of total, 38.1% of participants received seasonal influenza vaccine during the preceding season, 57.0% had willingness to accept A (H1N1) influenza vaccine at baseline, and 12.1% had received A (H1N1) influenza vaccine by the time of follow-up. After adjustment for potential confounding variables, people who had been vaccinated were significantly more likely to be living with an underlying disease (p = 0.001), to perceive high susceptibility to influenza (p = 0.03), to have willingness to pay even if the vaccine costs ≥ US$44 (p = 0.04), to have received seasonal influenza vaccine during the preceding season (p<0.001), and to have willingness to accept A (H1N1) influenza vaccine at baseline (p<0.001) compared to those who had not been vaccinated.Conclusions/SignificanceWhile studies have reported high rates of willingness to receive A (H1N1) influenza vaccine, these rates may not transpire in the actual practices. The uptake of the vaccine may be determined by several potential factors such as perceived susceptibility to influenza and sensitivity to vaccination cost in general population.
“…The hesitation of women to vaccinate when the second (after the vaccine against hepatitis B virus) anticancer vaccine became finally available has been also described in other vaccines. The most recent example is the vaccine against novel influenza A (H1N1), where, despite the acutely threatening nature of the condition and the high demand for a vaccine, the actual coverage rates after the vaccine became available remained generally low [15,16]. It appears that public uptake generally depends on a balance between fear of the disease and fear of the potential adverse effects of the vaccine [15,[17][18][19].…”
Apart from demographic factors which may favor or disfavor vaccine acceptability, the intention to vaccinate decreased significantly and the proportion of women rejecting vaccination for safety concerns increased significantly after the introduction of the vaccine, coinciding with isolated cases of negative publicity and highlighting the potential of misinformation by the media.
“…We also obtained vaccination status data on participants who refused to participate, which shows similar vaccination rates between the two groups. In addition, participants were recruited postpartum, therefore we were able to measure actual vaccine uptake and not just vaccination intention [70], an unreliable measure of actual vaccination status [71,72]. Nevertheless, the low number of respondents who were actually vaccinated may have limited the study power to identify other factors associated with vaccine uptake.…”
Low seasonal influenza vaccination uptake among Hong Kong pregnant women was related to a number of factors, all of which are amenable to interventions. Vaccination promotion strategies need to focus on encouraging health-care providers to discuss vaccination with their pregnant clients and in providing pregnant women with accurate and unbiased information about the risks of influenza infection and the benefits of vaccination.
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