Relationship between illness perception, fear of progression and quality of life in interstitial lung disease patients: A cross‐sectional study

Abstract

Aims and objectives:This study aimed to investigate whether fear of progression mediates the association between illness perception and quality of life among interstitial lung disease patients.Background: So far, the physiological treatment of interstitial lung disease is limited.In addition to immunosuppressants such as glucocorticoids, two anti-fibrosis drugs (pirfenidone and nintedanib) have shown moderately beneficial effects on slowing the progression of interstitial lung disease fibrosis. However, none of these drugs has shown reliable or strong beneficial effects on improving quality of life. Psychological care and mental health support strategies focusing on improving patients' quality of life are particularly important. Design: A cross-sectional study.Methods: A convenience sample of patients suffering from interstitial lung disease were enrolled from August to December 2019. Data including sociodemographic and clinical characteristics, illness perception, fear of progression and quality of life were collected. The descriptive analysis and Pearson correlations were analysed by SPSS 26.0 (IBM Corp.). PROCESS v3.4 (by Andrew F. Hayes) macro was applied to analyse the mediating effects. We used the STROBE checklist to report the results.Results: Both illness perception and fear of progression were correlated with quality of life. Fear of progression mediated the association between illness perception and quality of life. The indirect effect was 0.121, and the proportion of intermediary effect in the main effect was 26.36%. Conclusion:Interstitial lung disease patients experience relatively poor quality of life and fear of progression exerts a mediating role between illness perception and quality of life. Relevance to clinical practice:This study alerts medical staff to pay attention to negative illness perception and excessive fear, which is helpful to formulate effective interventions to manage interstitial lung disease patients' quality of life.

Anxiety and depression status in patients with idiopathic pulmonary fibrosis and outcomes of nintedanib treatment: an observational study

“…Thus, economic factors have a potential impact on the psychological state of IPF patients. In addition, the fearful experience brought by disease progression may likewise lead to anxiety and depression, especially in ILDs with poor quality of life [ 18 ]. Therefore, it is necessary to explore the factors associated with combined anxiety and depression in IPF and the effects of antifibrotic therapy on the psychological status of patients with IPF.…”

Correlation Analysis of Disease Perception, Ruminative Rumination, and Psychological Resilience in Elderly Patients with Acute Stroke

“…Illness perception is closely linked with disease progression and is considered malleable, encompassing both positive and negative perceptions. Previous research has indicated that positive Illness perception is associated with a higher quality of life [9,10];helping to alleviate disease suffering and regulate psychological health [11]. In contrast, negative Illness perception can reduce medication adherence [12] and cause psychological distress, affecting patients' choices in medical care [13].…”

Association between illness perception and social alienation among maintenance hemodialysis patients: The mediating role of fear of progression

“…The correlation between IP and social interaction has been demonstrated in many patients with chronic diseases. Prior investigations have established a compelling association between illness perception (IP) and social alienation across various patient cohorts, including those affected by interstitial lung disease [ 28 ], cancer [ 29 , 30 ], and nonepileptic seizures [ 31 ]. It is with this backdrop that we proffer a well-founded conjecture, hypothesizing an intrinsic correlation between IP and social alienation.…”