Relationship between human serum albumin and in-hospital mortality in critical care patients with chronic obstructive pulmonary disease

Li, Ma; Li, Hui-Yin; Shanglin, Chen; Li, Haiming; Zhanyi, Di; Wang, Shuchun; Meng, Bo; Murong, Lu

doi:10.3389/fmed.2023.1109910

Cited by 5 publications

(1 citation statement)

References 29 publications

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“…This study was based on the real-world study concept and included all COPD patients from the MIMIC-IV database. Our inclusion criteria were as follows: (1) Patients were older than 18 years and stayed in the ICU for more than 24 hours; [12][13][14] (2) Patients were diagnosed as COPD by ICD-9 codes (code = 49120, 49121, 49122) and ICD-10 codes (code = J44, J440, J441 and J442). Patients whose red cell, platelets, lymphocyte, hemoglobin levels were unavailable during the first day of ICU admission were excluded, as well as, the length of hospital time and ICU stay time was less than 24h.…”

Section: Selection Of Study Populationmentioning

confidence: 99%

Association of Red Cell Index and Hospital Mortality in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit: A Retrospective Cohort Study

Shi,

et al. 2023

COPD

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This study aims to explore the association between red cell index (RCI) and hospital mortality in Chronic Obstructive Pulmonary Disease (COPD) patients in the intensive care unit. Patients and Methods: This was a retrospective cohort research. The study included 821 COPD patients. Clinical data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database was conducted. Multivariate logistic regression analysis was used to assess the correlation between RCI and in-hospital mortality. Age, SOFA score, diabetes mellitus, cerebrovascular disease, congestive heart failure and mechanical ventilation were considered for subgroup analysis. Results: This study comprised 821 patients, of which 16.5% (124/821) suffered hospital mortality. In the multivariate logistic regression model, RCI was positively associated with hospital mortality, each unit increase in RCI was associated with a 3% increase in hospital mortality (odds ratio [OR] =1.03; 95% confidence interval [95CI%] =1.01-1.06). Meanwhile, compare with the lowest RCI group, the highest RCI groups tended to have higher risks of hospital mortality (OR [95% CI] 2. 33 [1.27-4.27]). Additionally, subgroup analysis result was persistent among all the groups. Conclusion: Higher RCI was positively associated with a higher risk of mortality in critically ill patients with COPD. Further investigation is necessary to confirm these findings.

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Section: Selection Of Study Populationmentioning

confidence: 99%

Association of Red Cell Index and Hospital Mortality in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit: A Retrospective Cohort Study

Shi,

et al. 2023

COPD

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Association between per- and polyfluoroalkyl substances exposure and prevalence of chronic obstructive pulmonary disease: The mediating role of serum albumin

Wang,

Zhang,

Zhang

et al. 2024

Science of The Total Environment

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Serum Albumin as Prognostic Marker for Older Adults in Hospital and Community Settings

Riviati,

Legiran,

Indrajaya

et al. 2024

Gerontology and Geriatric Medicine

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Serum albumin, known for its multifaceted role in health, is hypothesized to serve as a prognostic marker for older adults, both in hospital and community settings. Nine studies were included in the review, revealing consistent associations between low serum albumin levels and increased mortality risk in hospitalized older individuals. In community settings, low serum albumin levels were linked to higher mortality rates compared to those with normal levels. The synthesis of evidence underscores the potential of serum albumin as a prognostic marker for older adults, offering valuable insights for risk stratification and targeted interventions. While robust evidence supports its utility in hospital settings, further research is warranted in community settings to address current limitations and enhance the applicability of serum albumin as a prognostic tool. This review merges existing knowledge of the prognostic significance of serum albumin in older adults across hospital and community settings. The findings emphasize the importance of serum albumin as a potential prognostic marker, urging continued research efforts to refine its application in diverse healthcare contexts and improve outcomes for the aging population.

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Relationship between human serum albumin and in-hospital mortality in critical care patients with chronic obstructive pulmonary disease

Cited by 5 publications

References 29 publications

Association of Red Cell Index and Hospital Mortality in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit: A Retrospective Cohort Study

Association of Red Cell Index and Hospital Mortality in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit: A Retrospective Cohort Study

Association between per- and polyfluoroalkyl substances exposure and prevalence of chronic obstructive pulmonary disease: The mediating role of serum albumin

Serum Albumin as Prognostic Marker for Older Adults in Hospital and Community Settings

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