Relationship between gut microbiome and bone deficits in primary hyperparathyroidism: A proof-of-concept pilot study
Meric Coskun,
Afruz Babayeva,
Tugba Barlas
et al.
Abstract:Parathyroid hormone (PTH) interacts with components of the gut microbiota to exert its bone-regulating effects. This study aimed to investigate the gut microbial composition in patients with primary hyperparathyroidism (PHPT). Nine patients with PHPT and nine age-sex and body mass index-matched healthy controls were included. Gut microbial composition was assessed using 16S rRNA gene amplicon sequencing in both groups at baseline and one month after parathyroidectomy in the PHPT group. Data were imported into … Show more
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