“…In the Eastern Uttar Pradesh population the frequency of G allele was in the range of 58% to 70% [11][12][13]. MTHFR C677T gene polymorphism is known to be associated with predisposition for different types of cancers like-oral cancer [14], breast cancer [15,16], colorectal cancer [17,18], gastric cancer [19,20], lung cancer [21,22], pancreatic cancer [23,24], and bladder cancer [25,26]. Similarly MTRR A66G gene polymorphism is also found to be associated with various types of cancers such as-cervical cancer [27], lung cancer [28,29], meningioma [30], colorectal cancer [31,32], head and neck cancer [33], pancreatic cancer [23], and breast cancer [34].…”