Relationship between glycated hemoglobin levels at admission and chronic post-stroke fatigue in patients with acute ischemic stroke

Ouyang, Qingrong; Xu, Lei; Zhang, Yunwei; Huang, Luwen; Du, Yang; Yu, Ming

doi:10.1016/j.exger.2024.112395

Cited by 1 publication

(1 citation statement)

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“…Decreased hemoglobin levels can lead to local tissue hypoxia, resulting in decreased muscle strength, increased fatigue, and cognitive impairment in patients ( 41 ). Prolonged deficiency of hemoglobin, if left uncorrected, can further lead to anemia and even impairment of hematopoietic system function, increasing the risk of hypo-hemoglobinemia and malnutrition ( 42 ). Serum albumin is one of the most common proteins in human blood, synthesized by the liver.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and influencing factors of malnutrition in stroke patients with bulbar paralysis: a cross-sectional study in China

Zeng,

Liu,

Cai

et al. 2024

Front. Nutr.

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BackgroundAlthough malnutrition has been shown to influence the clinical outcomes of Stroke Patients with Bulbar Paralysis (SPBP), the prevalence and influencing factors have yet to be uncovered.ObjectiveThis study aims to assess the current prevalence and factors associated with malnutrition in SPBP.MethodsA multicenter cross-sectional investigation was conducted among SPBP in China from 2019 to 2021. Information was collected on basic information, health condition, diagnosis, treatment, neurological function, activities of daily living, swallowing function, and nutritional status. A multivariable logistic regression model was used to identify the factors that influenced nutritional status. ROC analysis was used to assess the predictive value of each independent influencing factor and the logit model.ResultsIn total, 774 SPBP were enrolled, and the prevalence of malnutrition was 60.59%. Pulmonary infection [aOR:2.849, 95%CI: (1.426, 5.691)], hemoglobin [aOR: 0.932, 95%CI: (0.875, 0.982)], serum albumin [aOR: 0.904, 95%CI: (0.871, 0.938)], total protein [aOR: 0.891, 95%CI: (0.819, 0.969)], prealbumin [aOR: 0.962, 95%CI: (0.932, 0.993)], and National Institute of Health Stroke Scale (NIHSS) scores [aOR: 1.228, 95%CI: (1.054, 1.431)] were independent factors associated with malnutrition in SPBP. ROC analysis revealed that the logit model had the best predictive value [area under the curve: 0.874, 95% CI: (0.812, 0.936); specificity: 83.4%; sensitivity: 79.3%; p < 0.05]. Subgroup analysis showed that the nutritional status in dysphagic SPBP was additionally influenced by swallowing function and nutrition support mode.ConclusionThe prevalence of malnutrition in SPBP was 60.59%. Pulmonary infection, hemoglobin level, and NIHSS score were the independent factors associated with malnutrition. Swallowing function and nutrition support mode were the factors associated with malnutrition in dysphagic SPBP.

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Section: Discussionmentioning

confidence: 99%