Relationship between frailty and cognitive decline in Chinese older patients with Alzheimer's disease: The mediating role of social contact

The prevalence and influencing factors of cognitive frailty in patients with maintenance hemodialysis in China: a meta-analysis

“…According to the search strategy, 2311 relevant literatures were initially detected, 2 literatures were obtained through other channels, 453 duplicate literatures were initially excluded, 1822 literatures were excluded after reading the title and abstract, 28 literatures were excluded after further reading the full text, and 10 literatures [17][18][19][20][21][22][23][24][25][26] were nally included, including 9 cross-sectional studies and 1 cohort study, as shown in Fig. 1.…”

“…This study included 9 cross-sectional studies [17][18][19][20][21][22][23][24][25] and 1 cohort study [26]. The quality evaluation criteria of the 9 cross-sectional studies (AHRQ) ranged from 6 to 9 points, which belonged to medium to high quality literature.…”

“…Sensitivity analysis of ≥ 10 literatures [17][18][19][20][21][22][23][24][25][26] was performed, and no single study was found to signi cantly affect the total effect size. After excluding any one study, there was no signi cant change in the combined results, so the results were considered to be stable.…”

Cross sectional association between cognitive frailty and disability among community-dwelling older adults: Focus on the role of social factors

“…Thus, subjective satisfaction with relationships including friends, community may be more influential on the health outcomes of older adults than the structural aspects of social relationships, which is supported by previous studies ( 39 , 40 ). Participation in social activities and social contacts was most consistently associated with preservation of global cognitive function ( 13 , 41 – 43 ) and prevention or slowing down of the process of physical frailty ( 44 ) across all study types. The theory of “use it or lose it” ( 45 ) suggests that the brain can be considered a muscle; thus, social activities may stimulate the brain and contribute to the preservation of cognitive function.…”

Longitudinal assessment of the relationship between frailty and social relationships among Japanese older adults: a random intercept cross-lagged panel model

“…A short-term study of [21] European countries categorized the types of social relationships to show that frail older adults preferred less-active types of social relationships to frequent, emotionally close, active ones [4]. Likewise, it was shown that the degree of social exposure with Alzheimer's disease could directly affect frailty among older Chinese people [19]. However, few studies have focused on associations in the opposite direction, i.e., impact of frailty on social relationships.…”