Relationship between feeding schedules and gastric distress during retinopathy of prematurity screening eye examinations

Pain-Relieving Interventions for Retinopathy of Prematurity: A Meta-analysis

“…In 8 studies (N = 421), researchers assessed crying time as an outcome. Four studies 31,34,35,48 were excluded from synthesis (Supplemental Table 3). Strube et al 35 found that feeding infants 1 hour before their eye examination reduced cry time compared with feeding 2 hours before (MD = 19%; P = .016).…”

“…Four studies 31,34,35,48 were excluded from synthesis (Supplemental Table 3). Strube et al 35 found that feeding infants 1 hour before their eye examination reduced cry time compared with feeding 2 hours before (MD = 19%; P = .016). Mehta et al 48 found no infants cried during the procedure when a speculum was not used, compared with 2 infants who cried when a speculum was used and 1 infant who cried when wide-field digital retina imaging was used but no statistical tests were conducted.…”

Literature review informs clinical guidelines for pain management during screening and laser photocoagulation for retinopathy of prematurity

“…In RCTs, comparisons between the use of individualised care methods, such as the Newborn Individualized Developmental Care and Assessment Program, as opposed to standard care, revealed no major differences, although the former approach was associated with a shorter time to recover from the stress of ROP screening. Feeding the newborn infant an hour before the test reduced the stress of the test (22,23). Quality of evidence: very low.…”

“…Numerous, different studies demonstrated that the combined use of nonpharmacological analgesia and local anaesthetics produced better results in terms of reducing pain. The recommended intervention may have few inconsequential side effects, even though it has not been shown in high-quality studies to be beneficial (19,20,23,26,(28)(29)(30)(31)(32)(33)(34)(35)(36)(37). Quality of evidence: low.…”