Relationship between Different Degrees of Compression and Clinical Symptoms in Patients with Myocardial Bridge and the Risk Factors of Proximal Atherosclerosis

Abstract

Objective. To explore the relationship between different degrees of compression and clinical symptoms in patients with the myocardial bridge and the risk factors of proximal atherosclerosis. Methods. The clinical data of 156 patients with the myocardial bridge who underwent selective coronary angiography in our hospital from December 2010 to December 2015 were collected. The patients were divided into Noble grade I group (102 cases) and Noble grades II-III group (54 cases) according to the degree of mural coronary artery systolic stenosis. According to the results of coronary angiography, 156 patients with the myocardial bridge were divided into an atherosclerosis group (the myocardial bridge combined with atherosclerosis at the proximal end of the myocardial bridge of simple wall coronary artery), 91 cases, and a control group (isolated myocardial bridge), 65 cases. The relationship between different degrees of compression and clinical symptoms in patients with the myocardial bridge was observed, and the logistic regression model was used to analyze the risk factors of proximal atherosclerosis in patients with the myocardial bridge. Results. The incidence of atherosclerotic stenosis, angina pectoris, and myocardial infarction in the proximal part of the myocardial bridge in the Noble grades II-III group was higher than that in the Noble grade I group ( P < 0.05 ). The differences in age, hypertension, and Noble classification between the two groups were statistically significant ( P < 0.05 ). The differences of total cholesterol (TC) and C-reactive protein (CRP) between the two groups were statistically significant ( P < 0.05 ). Multivariate analysis showed that age, hypertension, Noble grade, and CRP were all risk factors for proximal atherosclerosis in patients with the myocardial bridge ( P < 0.05 ). Conclusion. The more severe the compression of the myocardial bridge, the greater the risk of cardiovascular events for patients and the higher the incidence of atherosclerotic stenosis in the proximal part of the myocardial bridge. In addition, the occurrence of atherosclerosis in the proximal coronary artery of the myocardial bridge may be affected by age, hypertension, Noble grade, and CRP level.

Assessment of myocardial bridging and the pericoronary fat attenuation index on coronary computed tomography angiography: predicting coronary artery disease risk

“…The endothelial cell surfaces of the coronary artery in the proximal MB present rough worm-eaten-like defects. Platelets accumulate on the bare basement membrane, causing endothelial cells to detach from the basement membrane, leading to atherosclerotic plaques [22]. Therefore, there are several reasons to believe that the higher systolic compression of MB may have greater effects on the diastolic/systolic velocity ratio and would more easily lead to disturbances in blood flow and endothelial injury.…”

A Case of Symptomatic Myocardial Bridge Treated with Calcium Channel Blocker

“…The severity of the MB is correlated with the risk of cardiovascular events such as atherosclerotic stenosis in the proximal part of the MB and may be affected by age, hypertension, Noble grade, and CRP level. 11 The middle portion of LAD (Mid-LAD) was predominantly the site for MB in most cases, 12 , 13 which can be diagnosed through angiography demonstrating the milking effect on the overlying bridged segment.…”

Retracted: Relationship between Different Degrees of Compression and Clinical Symptoms in Patients with Myocardial Bridge and the Risk Factors of Proximal Atherosclerosis

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”