Relationship between dietary factors and recurrent aphthous stomatitis in China: a cross-sectional study

Abstract

Objective Recurrent aphthous stomatitis (RAS), a common oral mucosal disorder characterized by chronic, inflammatory, and ovoid ulcers, has a complex etiology. The purpose of the study was to investigate the specific dietary factors influencing the prevalence of RAS. Methods A total of 754 participants aged 18 to 59 years were enrolled in this descriptive cross-sectional study. An anonymous questionnaire was adopted to investigate the distribution of RAS, dietary factors, self-reported trigger factors, and therapeutic methods. Results Among all participants, the prevalence rate of RAS was 21.4%. Univariable analysis showed that fruit, dairy products, vegetables, and water, but not fried foods, fermented foods, spicy foods, and eggs, were preventive factors against RAS. After adjusting for age and sex, multivariable regression analysis suggested that fruit (adjusted odds ratio [aOR] = 0.430, 95% confidence interval [CI] = 0.218–0.847) and water (aOR = 0.294, 95% CI = 0.119–0.726) were protective factors against RAS. Conclusion This study found that the consumption of fruit and water was negatively associated with RAS. These results imply a potential adjunctive and complementary role of food in RAS treatment and some feasible means of RAS prevention.

Cardiovascular diseases, risk factors, and ulcer relapse in older adults with recurrent aphthous stomatitis: A retrospective cohort study

“…In fact, we demonstrated that the proportion of smoking history in the relapse group showed a 100% increase compared with that in the no-relapse group, although no association was found in this study. The association was also not signi cant when stratifying by spicy food intake habit, consistent with a cross-sectional study of patients aged 18-59 years [12]. Recent research has hypothesized that intake of high-calorie fried and spicy food is a risk factor for RAS [10].…”

Predisposing Factors for Recurrent Aphthous Stomatitis among Undergraduate Dental Students

“…Some of the vitamins and minerals found in vegetables and fruit function as antioxidants, and these can reduce the occurrence of disease or prevent the occurrence of lesions. 42 Predisposing factors for RAS caused by nutritional deficiencies when there are insufficient vegetables, fruits, and other foods in the diet can result in RAS. In this study, only limited questions related to predisposing factors for nutritional deficiency were asked.…”

Phyllanthus emblica fruits: a polyphenol-rich fruit with potential benefits for oral management

“…167 Fruits, dairy products, vegetables and water in the diet have been proven to be the prevention factors of RAU, and the intake of fruit and water is inversely associated with the incidence rate of RAU. 168…”