Relationship between diabetes control and pulmonary function in insulin-dependent diabetes mellitus

Ramirez, Luis C.; Nogare, Anthony Dal; Hsia, Connie C. W.; Arauz, Carlos; Butt, Irfan; Strowig, Suzanne M.; Schnurr-Breen, Laura; Raskin, Philip

doi:10.1016/0002-9343(91)90154-p

Cited by 70 publications

(60 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus decrease in muscular and recoiling forces of the respiratory system because of increased glycosylation is responsible for significant decrease in FEF 25-75%. Similar findings were observed in other studies [18,20]. The flow can also be decreased due to obstruction.…”

Section: Resultssupporting

confidence: 92%

“…In this study fasting and post meal blood glucose levels and HbA1c% were found to be significantly more in type 2 diabetics than the controls pointing to the fact that there was poor glycemic control. This may be because of irregular drug intake, inappropriate drugs, sub-dosing, overeating, lack of diabetic life style discipline, etc practiced by the patients [18]. HbA1c% is an indicator of diabetes control.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of Lung Function by Spirometry and Diffusion Study and Effect of Glycemic Control on Pulmonary Function in Type 2 Diabetes Mellitus Patients of the Eastern India

Zaman¹

2014

JCDR

View full text Add to dashboard Cite

Introduction: There are so many complications involving eyes, kidneys, lungs and nerves associated with diabetes. But, pulmonary complications are poorly characterized among eastern Indian diabetic populations. Aims and Objectives:To assess pulmonary function in patients with type 2 diabetes mellitus. To find out correlation of the pulmonary functions test variables with Glycemic control. Materials and Methods:Total of 60 type 2 diabetes patient of age between 35-55 y and same number of age and sex matched apparently healthy control individual were included in the present study. All subjects were evaluated for PFT by flow sensitive spirometer (RMS HELIOS-401), the spirometric parameters were measured as a percentage of predicted and DLCO (by single breath technique). HBA1c of all cases were measured and they were grouped according to HBA1c level (Group-a =>7%, Group-b =6%-7%, Group-c =<6%).Results: Significant differences in the spirometric parameters (FVC, FEV1/FVC) and diffusion capacity (DLCO% and DL/VA%) existed between cases and controls. There was a significant decrease in FVC, DLCO and DL/VA and significant increase in FEV1/FVC in that groups having HBA1c level >7% than the other groups. FEV1, FVC, DLCO, and DL/VA were negatively correlated with HbA1c where as FEV1/FVC has positive association with HbA1c. Conclusion:Significant deterioration of lung function and diffusing capacity was observed in type 2 diabetes patients with poor glycemic control.India [6][7][8][9]. The wide range of geographical and climatic conditions in a large country such as India may be associated with regional differences in lung function. Pulmonary complications are poorly characterized among eastern Indian diabetic populations. On this background this study was conducted on eastern India population for assessment of lung function in type 2 diabetes mellitus. AIMS AND OBjeCTIveS1. To assess pulmonary function in patients with type 2 diabetes mellitus.2. To find out correlation of the pulmonary functions test variables with Glycemic control. MATeRIAlS AND MeThODSEighty type 2 DM cases were randomly selected from patients attending Diabetic Following patients were excluded from the study: Smokers; history of respiratory diseases such as asthma, COPD, tuberculosis,

show abstract

Section: Resultssupporting

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Assessment of Lung Function by Spirometry and Diffusion Study and Effect of Glycemic Control on Pulmonary Function in Type 2 Diabetes Mellitus Patients of the Eastern India

Zaman¹

2014

JCDR

View full text Add to dashboard Cite

show abstract

“…The inverse relationship between DL CO /V A and HbA 1 c values observed in our children is nevertheless consistent with previous findings in adults, showing that diabetic patients with poor long-term metabolic control had lower DL CO values than comparable patients with long-term near-normoglycaemia [26]. We found the lowest DL CO /V A values in the three children who had initial retinopathy.…”

Section: Discussionsupporting

confidence: 92%

Diffusing capacity for carbon monoxide in children with type 1 diabetes

et al. 2004

View full text Add to dashboard Cite

Aims/hypothesis. Few data are available on lung dysfunction in children with diabetes. We studied the association of pulmonary function variables (flows, volumes and alveolar capillary diffusion) with disease-related variables in children with type 1 diabetes mellitus. Methods. We studied 39 children with type 1 diabetes (mean age 10.9±2.6 years, disease duration 3.6±2.4 years, insulin·kg −1 ·day −1 0.77±0.31) and 30 healthy control children (mean age 10.4±3.0 years). Pulmonary function tests included spirometry, N 2 wash-out and the single-breath diffusing capacity for carbon monoxide (DL CO Conclusions/interpretation. In children with type 1 diabetes, the diffusing capacity diminishes early in childhood and is associated with poor metabolic control. Although low DL CO /V A levels in these children probably reflect pulmonary microangiopathy induced by type 1 diabetes, other factors presumably influencing CO diffusion capacity measurements (e.g. a left shift in HbA 1 c resulting in high O 2 binding and low CO binding) could explain the apparent capillary and alveolar basal membrane dysfunction.Keywords Children · Lung function · Pulmonary gas exchange · Type 1 diabetes mellitus

show abstract

“…Pulmonary involvement in diabetes is increasingly reported, [26][27][28][29][30][31][32][33] and may have important consequences if patients have co-morbid COPD. Routine spirometry to monitor lung function may therefore be useful in the care of patients with diabetes, particularly those who smoke.…”

Section: Disease Monitoringmentioning

confidence: 99%

Spirometry in primary care case-identification, diagnosis and management of COPD

Price

Crockett

Arne

et al. 2009

Primary Care Respiratory Journal

View full text Add to dashboard Cite

SummaryChronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality worldwide, yet it remains significantly under-diagnosed. Systematic and opportunistic case-identification efforts in primary care, using questionnaires, careful assessment to identify symptoms, and follow-up spirometry, might improve diagnosis rates and enable earlier detection and management of COPD.The aims of spirometry performed for case-identification purposes are to exclude those patients with symptoms but normal lung function and identify those who require more complete investigation for COPD, including 'diagnostic standard' spirometry. Among patients with a confirmed diagnosis of COPD, spirometry monitoring is useful in identifying those with rapid deterioration in lung function who require further assessment. Spirometry in primary care can also support patient education and may encourage smoking cessation and treatment adherence.

show abstract

Relationship between diabetes control and pulmonary function in insulin-dependent diabetes mellitus

Cited by 70 publications

References 28 publications

Assessment of Lung Function by Spirometry and Diffusion Study and Effect of Glycemic Control on Pulmonary Function in Type 2 Diabetes Mellitus Patients of the Eastern India

Assessment of Lung Function by Spirometry and Diffusion Study and Effect of Glycemic Control on Pulmonary Function in Type 2 Diabetes Mellitus Patients of the Eastern India

Diffusing capacity for carbon monoxide in children with type 1 diabetes

Spirometry in primary care case-identification, diagnosis and management of COPD

Contact Info

Product

Resources

About