Relationship between Depression and Laryngopharyngeal Reflux

Joo, Young‐Hoon; Song, Youn-Su; Pae, Chi‐Un

doi:10.4306/pi.2017.14.2.226

Cited by 14 publications

(8 citation statements)

References 25 publications

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“…The sensation of sticking in the throat can appear continuously so that it can cause psychological disorders. [15][16][17] The results showed that there was no significant association between risk factors as gender, age, duration of symptoms, BMI, smoking and diet with psychiatric symptoms: depression, anxiety and stress. In another study also reported that there was no relationship between gender, age, BMI, and smoking habits and the patient's quality of life for LPR.…”

Section: Discussionmentioning

confidence: 92%

The association of risk factors with psychiatric symptoms and quality of life in laryngopharyngeal reflux disease patients

et al. 2020

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Background: Risk factors for laryngopharyngeal reflux (LPR), such as age, gender, BMI, smoking history and dietary habit affect the severity of LPR. These risk factors have a clinical impact on both social and emotional aspects, which can reduce the quality of life. Thus led the researchers to analyse association between these risk factors with psychiatric symptoms and quality of life for LPR sufferers.Methods: Analytical descriptive research with cross-sectional approach to LPR patients in ENT clinic RSUP Dr. Kariadi Semarang. Sixty six samples aged 18-60 years and met the criteria of the researcher were measured using the DASS 21 questionnaire and the RQS questionnaire. Statistical analysis used the chi-square test.Results: Obtained 66 subjects with a mean age of 45.1 years, there were more women than men (75.8%). Analysis of risk factors associated with depression found gender (p=1.000), age (p=1.000), duration of symptoms (p=1.000), BMI (p=0.132), smoking (p=0.452), and diet (p=1.000). Analysis of risk factors with anxiety obtained gender (p=0.340), age (p=0.743), duration of symptoms (p=0.085), BMI (p=0.322), smoking history (p=1.000), and diet (p=1.000). Analysis of risk factors with stress obtained gender (p=0.798), age (p=0.088), duration of symptoms (p=0.324), BMI (p=0.276), smoking history (p=0.606) and diet (p=0.538). Analysis of the gender association related to the quality of life LPR patients (p=0.032).Conclusions: Duration of symptoms, age, BMI, smoking history and diet were not associated with psychiatric symptoms and quality of life in LPR sufferers. Gender is not associated with psychiatric symptoms but is related to quality of life.

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Section: Discussionmentioning

confidence: 92%

The association of risk factors with psychiatric symptoms and quality of life in laryngopharyngeal reflux disease patients

et al. 2020

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“…One-third of LPR patients have anxiety and a significant reduction in social activities. 24 Patients with LPR have a significant increase in anxiety scores with Hospital Anxiety and Depression Scale (HADS). Patients might have anxiety over significant pathology, chronic nature of the disease, and lumps in their throat and are concerned about this symptom, whether it is an early sign of malignancy.…”

Section: Discussionmentioning

confidence: 99%

Proton pump inhibitors effect on the quality of life of patients with laryngopharyngeal reflux

Tamin

Zulka

Yunizaf

et al. 2022

Oto Rhino Laryn Indones

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Background: Laryngopharyngeal reflux (LPR) is a condition caused by retrograde flow of gastric contents to the larynx, pharynx, trachea, and bronchus, which can affect patients’ quality of life (QOL). Purpose: To evaluate the effect of proton pump–inhibitor (PPI) therapy on the quality of life of patients with laryngopharyngeal reflux (LPR). Methods: This randomized controlled trial study involved 52 patients with dysphagia. The short-form REFLUX-QUAL® questionnaire was used to assess QOL. The patients were given lansoprazole twice daily as early diagnostic method as well as a therapy for LPR. If improvement found, PPI therapy was continued for two months. Afterwards patients was randomly divided into continuous therapy group (n = 25) or an on-demand therapy group (n = 27). Results: There was no significant difference in gender, age group, or economic level among subjects in both groups. Treatment with PPIs both continuously and on-demand significantly improved patients’ QOL from 44.83 ± 19.11 to 83.37 ± 11.51 (p <0.001). Significant improvements occurred in almost all of eight QOL domains as compared at the start of and six months into PPI therapy (p <0.001); discomfort remained the exception as patients with LPR must continue to avoid certain foods, (p = 0.233). However, there was no significant difference between the continuous and on-demand therapy groups concerning improvements in the quality of life (p = 0.281). Conclusion: Treatment with PPIs either continuously or on-demand for six months significantly improved patients’ quality of life, with no significant difference between the two treatment groups.Keywords: proton pump inhibitor, PPI, quality of life, laryngopharyngeal reflux, LPRABSTRAKLatar belakang: Refluks laringofaring (RLF) adalah kondisi terjadinya aliran balik isi lambung ke laring, faring, trakea, dan bronkus yang dapat mempengaruhi kualitas hidup pasien. Terapi empiris Proton Pump Inhibitor (PPI) merupakan pendekatan diagnosis dan metode terapi untuk RLF. Tujuan: Penelitian ini bertujuan untuk mengevaluasi efektivitas pengobatan PPI terhadap kualitas hidup pasien RLF Metode: Penelitian secara uji acak terkendali ini melibatkan 52 pasien dengan keluhan disfagia. Digunakan Reflux-Qual Short form (RQS) untuk menilai kualitas hidup subjek. Pasien diberikan lansoprazole dua kali sehari sebagai diagnosis dini dan terapi untuk refluks. Apabila terdapat perbaikan, PPI diteruskan selama 2 bulan, kemudian pasien dibagi menjadi 2 grup secara acak. Kelompok pasien yang mendapatkan terapi secara kontinu terdiri dari 25 pasien, sedangkan kelompok terapi on-demand terdiri dari 27 pasien. Hasil: Tidak terdapat perbedaan signifikan pada jenis kelamin, usia, tingkat ekonomi antara pasien pada kelompok terapi kontinu dan on-demand. Pengobatan PPI secara kontinu dan on-demand secara signifikan meningkatkan kualitas hidup pasien dari 44,83 ± 19,11 menjadi 83,37 ± 11,51 (p<0,001). Selain itu, terdapat perbaikan yang signifikan pada hampir semua dari delapan domain kualitas hidup pada bulan keenam terapi PPI dibandingk an awal terapi, kecuali pada domain ketidaknyamanan pasien karena pasien harus menghindari makanan tertentu (p = 0,233). Namun, tidak ditemukan perbedaan yang signifikan pada kelompok terapi secara kontinu dan on-demand pada peningkatan kualitas hidup (p = 0,281). Kesimpulan: Pengobatan PPI secara kontinu dan on-demand selama 6 bulan secara signifikan meningkatkan kualitas hidup pasien RLF. Namun, tidak ada perbedaan yang signifikan antara kedua kelompok tersebut terhadap peningkatan kualitas hidup.Kata kunci: penghambat pompa proton, PPI, refluks laringfaring, refleks laringofaring, kualitas hidup

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“…22 In addition, laryngopharyngeal reflux symptoms, including cough, sore throat, and globus pharyngeus, may appear as a result of autonomic dysfunction, and are similar to the early symptoms of COVID-19. 23,24 Thus, it is possible that the incidence of patients with symptoms was high because there were many symptoms similar to COVID-19 symptoms resulting from the influence of psychological factors.…”

Section: Discussionmentioning

confidence: 99%

Safety and Effectiveness of an In-Hospital Screening Station for Coronavirus Disease 2019 in Response to the Massive Community Outbreak

Choi¹,

Ko²,

Song³

et al. 2021

RMHP

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Purpose: To evaluate the results of operating an in-hospital coronavirus disease 2019 screening station on an outpatient basis and to identify the effectiveness and necessity of such a screening station. Patients and Methods: This cross-sectional study included 1345 individuals who were tested for COVID-19 using real-time reverse transcription polymerase chain reaction (RT-PCR) at an in-hospital screening station on an outpatient basis. The subjects were healthcare workers (HCWs) with suspected COVID-19 symptoms or exposure to patients with confirmed COVID-19, caregivers at the hospital for complete enumeration, and patients who were scheduled to be admitted to a nonrestricted area in the hospital or to visit for outpatient treatment, but had suspected COVID-19 symptoms. The subjects were divided and compared as follows: HCW versus non-HCW groups and RT-PCR positive versus negative groups. Results: A total of 140 had symptoms, 291 wanted to be tested, and 664 were asymptomatic but were screened. Seven subjects had positive results for COVID-19. Compared with the non-HCWs, the HCWs were younger and had a lower rate of underlying medical conditions. In addition, there were more women, individuals with exposure to confirmed cases, and individuals with symptoms or those who just wanted to be tested. The frequency of all symptoms was high among the HCWs. The results of the logistic regression analysis showed that the HCWs were significantly associated with the presence of symptoms, having an odds ratio of 23.317 (confidence interval, 15.142-35.907L; P < 0.001). The positive group had a high rate of exposure to patients with confirmed COVID-19 and had more subjects with symptoms or those who wanted to be tested. Conclusion:In-hospital screening stations are a relatively safe way to protect and support HCWs and to reduce and manage the spread of infection within the hospital effectively during an outbreak in the community.

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Relationship between Depression and Laryngopharyngeal Reflux

Cited by 14 publications

References 25 publications

The association of risk factors with psychiatric symptoms and quality of life in laryngopharyngeal reflux disease patients

The association of risk factors with psychiatric symptoms and quality of life in laryngopharyngeal reflux disease patients

Proton pump inhibitors effect on the quality of life of patients with laryngopharyngeal reflux

Safety and Effectiveness of an In-Hospital Screening Station for Coronavirus Disease 2019 in Response to the Massive Community Outbreak

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