“…8,11,17 Trivedi et al, reported that an elevated fluoride level would affect higher levels of intelligence more vigorously than normal and low intelligence levels. 18 There was contrast reports presenting a statistically significant difference in IQ levels of children belonging to high, medium, and low fluoride areas, by Khan et al and Mondal et al 5,6 The functional and biochemical harm to the nervous system during the prenatal and development periods of infancy and childhood because fluoride can cross the blood brain barrier leading to lack of IQ in children exposed to high levels of fluoride is mainly; however, it is also due to factors involving variation in biological susceptibility, environmental conditions, and measurement errors. 19 Xiang et al, discussed about decreasing IQ with increasing age but reason is still not clear.…”