Abstract:Periodontitis is an inflammatory disease with a multifactorial etiology, triggered by the host's immune-inflammatory response to the periodontopathogens, manly gram-negative bacteria, present in the subgingival biofilm. Systemic conditions, such as diabetes mellitus (DM), can alter this response through immunological and microbiological changes. Studies have shown that DM promotes a dysbiotic pattern of biofilm, which may alter endotoxin content in the subgingival environment. Thus, the present study aims to e… Show more
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