Relationship Between Corneal Biomechanical Properties, Central Corneal Thickness, and Intraocular Pressure Across the Spectrum of Glaucoma

Kaushik, Sushmita; Pandav, Surinder Singh; Banger, Anupam; Aggarwal, Kanika; Ak, Gupta

doi:10.1016/j.ajo.2011.10.032

Cited by 122 publications

(101 citation statements)

References 34 publications

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“…We can obtain conclusions about the properties and data of ocular biomechanics from the parameters of this deformation. Biomechanical measurements are applied in the diagnosis of keratoconus [10,11], the effect studies of refractive surgeries [4][5][6], the evaluation of corneal collagen cross-linking [5,7,8] and also in the diagnosis of glaucoma [12,13]. Recently, a new device has been introduced which measures new ocular biomechanical properties.…”

Section: Discussionmentioning

confidence: 99%

Examination of ocular biomechanics with a new Scheimpflug technology after corneal refractive surgery

Hassan¹,

Módis²,

Szalai³

et al. 2014

Contact Lens and Anterior Eye

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a b s t r a c tPurpose: To analyze the early results of a new device measuring ocular biomechanics after corneal refractive surgery. Patients and methods: Thirty nine refractive surgery patients were enrolled in the study (age: 32.6 ± 9.9 years). Laser in situ keratomileusis (LASIK) was performed on 52 eyes of 26 patients and photorefractive keratectomy (PRK) was done on 26 eyes of 13 patients. Ten device-specific biomechanical parameters, intraocular pressure (IOP) and pachymetry were measured preoperatively and at day 1, week 1 and month 1 after the surgeries with a new technology based on Scheimpflug imaging (CorVis ST, Oculus). Results: In case of LASIK, the day after the procedure, radius values showed significant differences compared to preoperative data. One month after surgery, radius values, velocity of the second applanation and pachymetry showed significant differences compared to preoperative data. In case of PRK, the day after the procedure, significant differences in IOP, maximum amplitude at the apex, A1 time, A2 velocity and highest concavity time were measured. After 1 month of PRK, there were no differences in the parameters compared to preoperative data except pachymetry. Conclusions: We observed that some specific biomechanical parameters changed measured with CorVis ST after LASIK and PRK, in the early postoperative time. However, most of these parameters remain unchanged after one month of LASIK and PRK compared to preoperative data.

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Section: Discussionmentioning

confidence: 99%

Examination of ocular biomechanics with a new Scheimpflug technology after corneal refractive surgery

Hassan¹,

Módis²,

Szalai³

et al. 2014

Contact Lens and Anterior Eye

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“…2,3 With the introduction of ORA, an emphasis has been laid on the biomechanical measurements of the cornea in glaucoma diagnosis and in the assessment of the outcomes of refractive surgeries and corneal collagen cross-linking therapies. [4][5][6][7][8][9][10][11] Already the first publication reported differences in the parameters measured with ORA in healthy and keratoconus eyes and in those subsequent to refractive surgeries. 12,13,14 Recently, a new device called CorVis ST (Corneal Visualization Scheimpflug Technology, CorVis ST, Oculus Inc., Wetzlar, Germany) has been introduced that uses a high intensity air impulse for biomechanical measurements applying an ultra high-speed Scheimpflug camera.…”

Section: Introductionmentioning

confidence: 99%

Repeatability of Ocular Biomechanical Data Measurements With a Scheimpflug-Based Noncontact Device on Normal Corneas

Németh¹,

Hassan²,

Csutak³

et al. 2013

J Refract Surg

114

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any of the instruments used in this study. Flattest and steepest keratometric data and also IOP showed highly significant correlation with the ten specific CorVis ST parameters. Conclusions:The novel technique measuring ocular biomechanical properties showed high repeatability for only IOP and pachymetric data determined in our study. Single measurements are not reliable in case of the ten device-specific parameters. The equipment allows for conducting clinical examinations, and screenings of surgeries altering ocular biomechanical properties with some form of averaging of multiple measurements.

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“…This overlap of CH values presents major challenges when using ORA as a diagnostic tool (5,10). However, CH and CRF are accepted as pressure-independent risk factors for glaucoma (10). Lower the CH value higher the risk for glaucoma is.…”

Section: Discussionmentioning

confidence: 99%

Anterior segment and corneal biomechanics of achondroplasia patients

et al. 2018

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Herein the anterior segment findings with Pentacam and corneal biomechanics with Ocular Response Analyser of 4 genetically proven cases of achondroplasia are reported. Four patients with heterozygous gain of function p.G380R mutation in fibroblast growth factor Receptor 3 (FGFR3) gene were evaluated. Central corneal thickness was higher than normal in both eyes of one patient, and corneal hysteresis and corneal resistance factor was lower in three eyes of two patients with accompanying high intraocular pressure readings. As a result, the affection of FGFR3 in achondroplasia patients might cause changes in central corneal thickness, corneal hysteresis and corneal resistance factor.

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Relationship Between Corneal Biomechanical Properties, Central Corneal Thickness, and Intraocular Pressure Across the Spectrum of Glaucoma

Cited by 122 publications

References 34 publications

Examination of ocular biomechanics with a new Scheimpflug technology after corneal refractive surgery

Examination of ocular biomechanics with a new Scheimpflug technology after corneal refractive surgery

Repeatability of Ocular Biomechanical Data Measurements With a Scheimpflug-Based Noncontact Device on Normal Corneas

Anterior segment and corneal biomechanics of achondroplasia patients

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