Relationship between consanguinity and depression in a south Indian population

Rao, TS Sathyanarayana; Prabhakar, A. K.; Rao, K. S.; Sambamurthy, K.; Asha, M. R.; Ram, Dushad; Nanda, Ananya

doi:10.4103/0019-5545.44906

Cited by 9 publications

(4 citation statements)

References 17 publications

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“…Likewise consanguinity seemed to be associated with depression only on bivariate testing. Consanguineous marriages are fairly prevalent in South India and clinical observations have reported a high prevalence of depression in such communities (61) which could be genetically driven (62). A major catastrophic event in the past 1 year was an important risk factor which was significantly associated with prenatal depression in this study; this is consistent with the study results reported by Leigh et al (63) and Shakeel et al (58).…”

Section: Discussionmentioning

confidence: 99%

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Prenatal Depression and Its Associated Risk Factors Among Pregnant Women in Bangalore: A Hospital Based Prevalence Study

Sheeba

Nath

Metgud

et al. 2019

Front. Public Health

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Background: Depression is the commonest psychological problem that affects a woman during her perinatal period worldwide. The risk of prenatal depression increases as the pregnancy progresses and clinically significant depressive symptoms are common in the mid and late trimester. There is a paucity of research on depression during the prenatal period in India. Given this background, the present study aimed to assess the prevalence of prenatal depression and its associated risk factors among pregnant women in Bangalore, Southern India. Methods: The study was nested within an on-going cohort study. The study participants included 280 pregnant women who were attending the antenatal clinic at Jaya Nagar General Hospital (Sanjay Gandhi Hospital) in Bangalore. The data was collected by using a structured questionnaire which included. Edinburgh Postnatal Depression Scale (EPDS) to screen for prenatal depression. Results: The proportion of respondents who screened positive for prenatal depression was 35.7%. Presence of domestic violence was found to impose a five times higher and highly significant risk of developing prenatal depression among the respondents. Pregnancy related anxiety and a recent history of catastrophic events were also found to be a positive predictors of prenatal depression. Conclusion: The high prevalence of prenatal depression in the present study is suggestive of its significance as a public health problem. Health care plans therefore can include screening and diagnosis of prenatal depression in the antenatal care along with other health care facilities provided.

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Section: Discussionmentioning

confidence: 99%

“…Research done in other countries reportedly point toward an interconnection between obesity and depression (67, 68). The causal pathway could include inflammation (62), hormonal imbalance (69), or sleep disturbance (70).…”

Section: Discussionmentioning

confidence: 99%

Prenatal Depression and Its Associated Risk Factors Among Pregnant Women in Bangalore: A Hospital Based Prevalence Study

Sheeba

Nath

Metgud

et al. 2019

Front. Public Health

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“…Mansour (2009) finds genuine brain disorder causing violent temperament and behavior. Rao (2009) and Bener (2017) point out many other common mental diseases which are related to cousin marriages. These may be depression, anxiety and violent behaviors.…”

Section: Introductionmentioning

confidence: 99%

People’s Perception about Consanguineous Marriages and Child Health Issues: A Case Study in Gujranwala

Rizwana¹

2020

PSSR

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“…[ 5 ] In fact, genetic studies as such in respect of psychiatric disorders are very scarce in our country. We could find a pilot study to find the association of consanguinity and depression[ 6 ] and a pedigree study on the genetics of affective disorders. [ 7 ] There is a need to encourage genetics-based research in India to find out association of genetic factors with psychiatric disorders.…”

mentioning

confidence: 99%