Relationship between bone mass by densitometry and by histomorphometry in primary hyperparathyroidism and in osteoporosis

Anabolic Actions of Parathyroid Hormone on Bone*

“…Thus, in primary hyperparathyroidism, pure cancellous bone increases while cortical bone decreases, although the possibility that cancellous bone at different skeletal sites responds differently to PTH cannot be ruled out (211). Furthermore, indices of cancellous bone mass and structure (cancellous bone volume, trabecular number, trabecular separation) at the iliac crest were correlated with BMD at the spine, with its higher cancellous component, but not at the hip and wrist at least in women with primary hyperparathyroidism (212,213). The cumulative data assembled in our laboratory and by others on bone mass and structure in primary hyperparathyroidism have shown that there is a maintenance or even an increase of cancellous bone volume with a conservation of cancellous microarchitecture and preserved or even increased connectivity of trabecular plates.…”