“…They 2 concluded that larger, preferably prospective, studies were needed to confirm and update their findings. Recently, in 2023, Demirel and Dilek 3 published, a study entitled “Relationship between body composition and PBRM1 mutations in clear cell renal cell carcinoma: a propensity score matching analysis” in the Journal of the Brazilian Medical Association 3 , in which they retrospectively examined the relationship between body muscle and adipose tissue composition in clear cell renal cell carcinoma patients with polybromo-1 protein (PBRM1) 4 gene mutation 3 . The study 3 concluded that normal attenuation muscle area is greater in patients with PBMR1 mutation, even after propensity score matching 3 .…”