Relationship between baroreceptor cardiac reflex sensitivity and pain experience in normotensive individuals

Duschek, Stefan; Mück, I.; Paso, Gustavo A. Reyes del

doi:10.1016/j.ijpsycho.2007.03.012

Cited by 61 publications

(37 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In contrast to other studies [31], [57], [58], [59] depressive symptoms, though being somewhat higher in females then in males, did not significantly differ between sexes, which was also observed in regard to catastrophising. The failure to find sex differences may be blamed on the overall low level of depression and catastrophising found in our student sample and on the level of androgyny in the sample with the average androgyny score close to zero.…”

Section: Discussioncontrasting

confidence: 99%

“…As they are only crude indicators of the hormonal state, hormonal influences on pain cannot be ruled out by our study. It was confirmed that blood pressure is negatively associated with pain intensity, thus corroborating the assumptions of the central inhibitory effect of blood pressure via baroreceptor activity [57]. It was also strongly correlated to sex, with females showing a lower systolic blood pressure.…”

Section: Discussionsupporting

confidence: 64%

See 1 more Smart Citation

The effects of sex and gender role on responses to pressure pain

Kröner‐Herwig

Gaßmann²,

Tromsdorf³

et al. 2012

GMS Psycho-Social-Medicine; 9:Doc01; ISSN 1860-5214

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 64%

The effects of sex and gender role on responses to pressure pain

Kröner‐Herwig

Gaßmann²,

Tromsdorf³

et al. 2012

GMS Psycho-Social-Medicine; 9:Doc01; ISSN 1860-5214

View full text Add to dashboard Cite

“…These findings are in accordance with the results reported by Duschek et al [10] and Reyes del Paso et al [2]. Those authors found an inverse relationship between BRS and the subjective perception of pain measured by ratings of analogue visual scale (AVS).…”

Section: Discussionsupporting

confidence: 92%

Association between baroreflex function and pressure pain threshold in women with fibromyalgia

Andrade

Zamunér

Forti

et al. 2014

2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)

View full text Add to dashboard Cite

The aim of this study is to evaluate the relationship between baroreflex function and pain in women with fibromyalgia syndrome (FMS). Ten women with clinical diagnosis of FMS took part in the research. The ECG and blood pressure were continuously recorded on a beat to beat basis in supine and orthostatic postures. Coherence between SAP and RR variability (K 2 SAP-RR ) and baroreflex function (index α) were quantified. Pressure pain threshold (PPT) was determined at 18 specific tender points distributed all over the body, using a digital algometer. Correlation analysis showed positive relationship between PPT and K 2 SAP-RR sampled at high frequency (HF) band in the orthostatic posture (r = 0.67; p = 0.03). This result suggests that the higher is the coupling between SAP and RR series in HF band during orthostatic posture, the higher is the pressure needed to FMS participants to begin feeling pain.

show abstract

“…As predicted, the decrease in baroreflex sensitivity in our mouse model of CMP was accompanied by a 2-fold increase in blood pressure variability. Furthermore, activation of arterial baroreceptors and vagal afferents reflexively inhibit nociception in animals and humans [9;71], and spontaneous baroreflex sensitivity is inversely related to severity of pain in humans [14;24;72;73]. To our knowledge, the possibility that blood pressure variability may contribute to CMP has not been investigated previously.…”

Section: Discussionmentioning

confidence: 99%

Exercise prevents development of autonomic dysregulation and hyperalgesia in a mouse model of chronic muscle pain

Sabharwal

Rasmussen

Sluka

et al. 2016

Pain

View full text Add to dashboard Cite

Chronic musculoskeletal pain (CMP) conditions, like fibromyalgia, are associated with widespread pain and alterations in autonomic function. Regular physical activity prevents development of CMP and can reduce autonomic dysfunction. We tested if there were alterations in autonomic function in sedentary mice with CMP, and if exercise reduced the autonomic dysfunction and pain induced by CMP. CMP was induced by two intramuscular injections of pH 5 in combination with a single fatiguing exercise task. A running wheel was placed into cages so that the mouse had free access for either 5 days or 8 weeks (exercise groups) and these animals were compared to sedentary mice without running wheels. Autonomic function and nociceptive withdrawal thresholds of the paw and muscle were assessed before and after induction of CMP in exercised and sedentary mice. In sedentary mice, we show decreased baroreflex sensitivity, increased blood pressure variability, decreased heart rate variability and decreased withdrawal thresholds of the paw and muscle 24h after induction of CMP. There were no sex differences after induction of the CMP in any outcome measure. We further show that both 5 days and 8 weeks of physical activity prevent the development of autonomic dysfunction and decreases in withdrawal threshold induced by CMP. Thus, this study uniquely shows development of autonomic dysfunction in animals with chronic muscle hyperalgesia that can be prevented with as little as 5 days of physical activity, and suggest that physical activity may prevent the development of pain and autonomic dysfunction in people with CMP.

show abstract

Relationship between baroreceptor cardiac reflex sensitivity and pain experience in normotensive individuals

Cited by 61 publications

References 56 publications

The effects of sex and gender role on responses to pressure pain

The effects of sex and gender role on responses to pressure pain

Association between baroreflex function and pressure pain threshold in women with fibromyalgia

Exercise prevents development of autonomic dysregulation and hyperalgesia in a mouse model of chronic muscle pain

Contact Info

Product

Resources

About