Relationship between Aortic Arch Calcification, Detected by Chest X-Ray, and Renal Resistive Index in Patients with Hypertension

Abstract

Objective: Aortic arch calcification (AAC) is a surrogate marker for arterial stiffness and hypertension-related vascular damage. Renal resistive index (RRI), a renal Doppler ultrasonography parameter, is used to assess renal hemodynamics. In this study, we aimed to evaluate the relationship between RRI and AAC in patients with hypertension. Methods: Patients with hypertension underwent a chest X-ray and re nal Doppler ultrasonography. They were divided into two groups according to RRI (group 1: RRI ≥0.70; group 2: RRI < 0.70). Two examiners, blinded to the findings of RRI, reviewed the AAC in these patients. The kappa value was detected to be 0.781 and a p value < 0.001 was considered significant. Results: The study included 289 hypertensive patients (mean age 63.87 ± 11.38 years). In 53.6% (n = 155) of the study subjects, RRI was observed to be ≥0.70. Patients with RRI ≥70 were older and had more prevalent AAC as well as left ventricular hypertrophy. A multiple linear regression analysis was carried out to test whether presence of AAC significantly predicted RRI. The results of the regression analysis indicated that presence of AAC significantly predicted RRI (β = 0.053; p < 0.001). Conclusions: A strong and independent relationship was found between AAC on chest X-ray and RRI in patients with hypertension.

Comparison of renal arterial resistive index in type 2 diabetic nephropathy stage 0-4

“…Thus, increasing the excretion of albumin has led to an increase in the resistance of the renal interlobular arteries. These findings are consistent with the results of many studies, 29,32,48,49 which most studies emphasize RI role in reflecting intra-renal microvascular characteristics. 50,51 Albuminuria (rate ≥30 mg/24 h) has been defined to be a marker of kidney damage (National Kidney Foundation, 2002).…”

“…52,53 Microalbuminuria has been demonstrated to be valuable for predicting diabetic nephropathy and could serve as a clue for the onset of kidney damage. 49 The association of RI with microalbuminuria in some investigations could suggest the impact of increased pulsatility on aorta, resulting in accelerating the gradual microvascular damage. 51 As indicated previously, albuminuria was linked to RI, where its increase was observed in subjects with macroalbuminuria (>300lg/mg creatinine) as compared with normoalbuminuria.…”

Obstrüktif Uyku Apneli Hastalarda Metabolik Sendrom İçin Göğüs Radyografisi Üzerinde Güçlü Bir İpucu: Aortik Ark Kalsifikasyonu

“…Vascular calcification increases with age and has debilitating effects on the cardiovascular system. It results in increased arterial stiffness and myocardial workload, and impaired diastolic coronary perfusion, resulting in a higher risk of stroke, hypertension, myocardial infarction, diabetes mellitus, renal failure, hyperlipidemia, and left ventricle hypertrophy (18)(19)(20)(21). Consistent with previous studies, we found that AAC increased with age and was significantly associated with hypertension, diabetes, hyperlipidemia and left ventricular hypertrophy, in addition to being negatively correlated with GFR.…”

Predicting Prolonged Hospitalization and Supplemental Oxygenation in Patients with COVID-19 Infection from Ambulatory Chest Radiographs using Deep Learning

“…Even before advanced deep learning techniques, CXRs have been shown to correlate with the risk of stroke, vascular resistance, and atherosclerosis through the identification of aortic calcification 27 , 28 , 29 . Similar deep learning methods were used on two large sets of frontal CXRs and demonstrated predictive power for mortality [29] .…”