Relationship among Corneal Biomechanics, Anterior Segment Parameters, and Geometric Corneal Parameters

Abstract

Purpose. To investigate the relationship between corneal biomechanical parameters, anterior segment parameters, and geometric corneal parameters in a healthy Caucasian group. Methods. This retrospective study included the healthy eyes with best corrected visual acuity of at least 20/40 of 122 Caucasian subjects. The anterior segment parameters and geometric corneal parameters such as corneal volume, central corneal thickness, horizontal and vertical corneal radii, anterior and posterior steep, and flat keratometric values were measured with a Scheimpflug camera. The biomechanical properties were measured with Ocular Response Analyzer. Results. One hundred and twenty-two healthy Caucasian subjects (67 males, 55 females) with a mean age of 45.32 ± 20.23 were enrolled. Both corneal hysteresis and corneal resistance factor were positively correlated with CCT (r = 0.529, p < 0.001; r = 0.638, p < 0.001) and CV (r = 0.635, p < 0.001; r = 0.579, p < 0.001) and negatively correlated with age (r = −0.373, p < 0.001; r = −0.249, p < 0.001). Both in age-gender and multivariate models, CH and CRF had statistically significant negative association with the posterior steep K value. Conclusions. CH and CRF are negatively correlated with posterior steep and average posterior K values.

Correlation Between Corneal Biomechanics and Anterior Segment Parameters in Healthy Saudi Females

“…CH and CRF in the current study showed no signi cant association with ACD and ACV in all eyes which agreed with Hwang et al 7 However, this nding was not in agreement with Çevik et al 2016 10 who reported positive associations between ACD and CRF and Chang et al 13 who con rmed a signi cant association between ACD measured by the IOLMaster and CH only not CRF. On the other hand, mild myopic eyes (63 eyes) in our study showed a highly signi cant positive correlation between IOP g and ACV.…”

“…On the other hand, the association between ORA parameters and keratometric values for mild myopic eyes (63 eyes) in this study found a signi cant positive correlation between ASKV and each of CH and CRF. Çevik et al 2016 10 reported a negative correlation between CH, CRF with both posterior steep and average posterior values. Furthermore, many studies 7,8,9,[13][14][15][16][17] reported an association between mean k and CH only.…”

“…Hwang et al 2013 7 found that CV was positively correlated with CH, but not CRF. However, Çevik et al 2016 10 reported positive correlations between CH, CRF, and CV and negative correlations between CH, CRF and both of posterior steep and average posterior values.…”

“…1 Anterior segment parameters such as central corneal thickness (CCT), thinnest corneal thickness (TCT), apex corneal thickness (Apex CT), corneal volume (CV), anterior chamber depth (ACD), anterior chamber volume (ACV) and corneal astigmatism (CA) can be measured by Pentacam which is a Scheimp ug imaging device. 2 Many studies [3][4][5][6][7][8][9][10] investigated the correlation between corneal biomechanics and anterior segment parameters in healthy eyes and demonstrated a strong correlation between CH, CRF with CCT. Hwang et al 2013 7 found that CV was positively correlated with CH, but not CRF.…”

The Influence of the Cornea on Intraocular Pressure Measurement by ICARE PRO and ORA

“…Protože je CCT pozitivně korelována s tuhostí rohovky (tlustší rohovky jsou i tužší, viz např. [5,35,5]), lze na základě vzájemného vztahu pokládat vliv CCT pozorovaný v naší i v jiných studiích za odraz vlivu tuhosti rohovky. Měření CH však nebylo do této práce zahrnuto.…”