Relation of the Ankle Brachial Index to Left Ventricular Ejection Fraction

Relation of Ankle Brachial Index to Left Ventricular Ejection Fraction in Diabetic Patients

“…Because left ventricular (LV) systolic function has been shown to influence arterial wave reflective properties [10], it is presumed that the ABI would reflect LV systolic function, as well as atherosclerosis. Recent study showed that the ABI might be influenced by LV systolic function, independent of coronary disease [11]. However this is the first study reporting this probability.…”

“…ABI was independently related to LVEF [11]. Results of current study showed that ankle brachial index would be influenced by left ventricular ejection fraction in diabetics, and the diabetes period as well as the evaluation and monitoring of cardiovascular risk in patients should be considered together.…”

“…Recent study showed that the ABI might be influenced by LV systolic function independent of coronary disease [11]. Ward et al [18] in the study of 204 patients with symptomatic PAD found that LVEF less than 55% among patients with low ABI is more common than normal ABI.…”

The Ankle-Brachial Index Is Related to Left Ventricular Ejection Fraction in Bonnet Macaques

“…The diffuse nature of atherosclerosis poses the coexistence of PAD and coronary artery disease leading to myocardial infarction and LV dysfunction as a possible explanation for the LVEF-ABI association. However, three findings led us to conclude that a direct hemodynamic effect of depressed LV systolic function on ABI was more likely: (1) similar correlations between LVEF and ABI in patients with and without CAD; (2) CAD was insignificant as an interaction variable on multivariate analysis, and (3) not only was lower ABI associated with lower LVEF, but also higher ABI values were associated with higher LVEF [7]. However, to date, no study has systematically evaluated subjects for the presence of PAD by angiography.…”

“…Since left ventricular (LV) systolic function has been shown to influence arterial wave reflective properties [6,] we previously studied the relation between ABI and LV systolic function in humans and found ABI to be independently associated with LV ejection fraction (LVEF) in community patients referred for ABI studies [7]. Since then, several groups have confirmed this relationship in different cohorts including elderly patients with ischemic heart disease, diabetics and nondiabetics, and in subjects with atrial fibrillation [8,9,10,11,12].…”