Relation of systemic arterial pulse pressure to coronary atherosclerosis in patients with mitral stenosis

Lee, Tsung-Ming; Yueh-Juh, Lin; Su, Sheng‐Fang; Chien, Kuo–Liong; Chen, Ming-Fong; Liau, Chiau-Suong; Lee, Yuan‐Teh

doi:10.1016/s0002-9149(97)00599-7

Cited by 16 publications

(2 citation statements)

References 18 publications

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“…Many studies have so far investigated the association between PP and CAD. Lee et al [16] were the first to explore the association between high PP and the presence of CAD. PP was measured both by non-invasive sphygmomanometer and invasive catheterization before surgical intervention in 159 patients of mitral valve stenosis.…”

Section: Discussionmentioning

confidence: 99%

Brachial pulse pressure is associated with the presence and extent of coronary artery disease in stable angina patients: a cross-sectional study

Peng

2020

BMC Cardiovasc Disord

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Background: Previous epidemiological evidence has identified many risk factors for coronary artery disease (CAD). Pulse pressure (PP) was reported to be associated with CAD. However, more attention was paid to aortic PP than to brachial PP. This cross-sectional study aimed to investigate the direct relationship between brachial PP and the presence and extent of CAD in stable angina patients. Methods: We recruited a total of 1118 consecutive patients with stable chest pain suspected of CAD. After screening with exclusion criteria, 654 patients were finally included in our study. Every patient underwent both blood pressure measurement and selective coronary angiography. Univariate and multivariate analysis were performed to analyze the association between PP and the presence and extent of CAD. Results: This study revealed that brachial PP was an independent correlate of multivessel CAD. In multivariate generalized linear regression model, increasing brachial PP (per 1 mmHg) were associated with the increased number of diseased vessels (β = 0.01, SE = 0.00, P < 0.0001). Binary logistic regression analysis further confirmed this association. The risk of multivessel CAD increased significantly in patients with brachial PP ≥ 60 mmHg (OR = 1.69, 95% CI = 1.14-2.48, P = 0.0084) and as per 1 mmHg increased in brachial PP (OR = 1.02, 95% CI = 1.01-1.03, P = 0.0002), independent of age, gender, body mass index (BMI), smoking, diabetes, hypercholesterolemia and creatinine (Cr). This association was still of statistical significance in subgroup analysis of hypertension and diabetes. Conclusion: Increasing brachial PP was significantly and independently associated with increased risk of multivessel coronary disease in stable angina patients. The association of brachial PP with CAD was more pronounced in hypertension group than in non-hypertension one.

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Section: Discussionmentioning

confidence: 99%

Brachial pulse pressure is associated with the presence and extent of coronary artery disease in stable angina patients: a cross-sectional study

Peng

2020

BMC Cardiovasc Disord

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“…The principal underlying pathophysiologic mechanism is considered to a mechanical one, related to pulse pressure 28 . Wide pulse pressure has been reported to be associated with increased cardiac events 29–33 .…”

Section: Discussionmentioning

confidence: 99%

Relationship of Hypertension to Coronary Atherosclerosis and Cardiac Events in Patients With Coronary Computed Tomographic Angiography

et al. 2017

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Hypertension is an atherosclerosis factor and is associated with cardiovascular risk. We investigated the relationship between hypertension and the presence, extent and severity of coronary atherosclerosis in coronary computed tomography angiography as well as cardiac events risk. Of 17181 patients enrolled in the CONFIRM registry who underwent ≥64-detector row coronary computed tomography angiography, we identified 14803 patients without known coronary artery disease. Of these, 1434 hypertensive patients were matched to 1434 patients without hypertension. Major adverse cardiac events risk of hypertension and no-hypertension patients was evaluated with Cox proportional hazards models. The prognostic associations between hypertension and no-hypertension with increasing degree of coronary stenosis severity (non-obstructive or obstructive ≥50%) and extent of coronary artery disease (segment involvement score 1–5, >5) was also assessed. HT patients less commonly had no coronary atherosclerosis and more commonly had non-obstructive as well as one, two, and three vessel disease than the no-hypertension group. During a mean follow-up of 5.2±1.2 years, 180 experienced cardiac events, with 104 (2.0%) occurring in the hypertension group and 76 (1.5%) occurring in the no-hypertension group (Hazard ratios 1.4, 95% confidence intervals 1.0–1.9). Compared to no-hypertension patients without coronary atherosclerosis, hypertension patients with no coronary atherosclerosis and obstructive coronary disease tended to have higher risk of cardiac events than the no-hypertension group. Similar trends were observed with respect to extent of coronary artery disease. Compared to no-hypertension patients, hypertensive patients have increased presence, extent, and severity of coronary atherosclerosis and tend to have an increase in major adverse cardiac events.

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Aortic pulse pressure is related to the presence and extent of coronary artery disease in men undergoing diagnostic coronary angiography: a multicenter study

Danchin

Bénétos

Lopez‐Sublet

et al. 2004

American Journal of Hypertension

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Relation of systemic arterial pulse pressure to coronary atherosclerosis in patients with mitral stenosis

Cited by 16 publications

References 18 publications

Brachial pulse pressure is associated with the presence and extent of coronary artery disease in stable angina patients: a cross-sectional study

Brachial pulse pressure is associated with the presence and extent of coronary artery disease in stable angina patients: a cross-sectional study

Relationship of Hypertension to Coronary Atherosclerosis and Cardiac Events in Patients With Coronary Computed Tomographic Angiography

Aortic pulse pressure is related to the presence and extent of coronary artery disease in men undergoing diagnostic coronary angiography: a multicenter study

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