Relation of Highly Sensitive Cardiac Troponin T in Hypertrophic Cardiomyopathy to Left Ventricular Mass and Cardiovascular Risk

High T2-weighted signal intensity is associated with elevated troponin T in hypertrophic cardiomyopathy

“…In case of a discrepancy between the treating physician and the investigators, a third opinion of an independent reviewer was decisive. Patients with known coronary disease, stroke, aortic stenosis, previous septal reduction therapy, contraindication for CMR imaging or renal impairment (defined as modification of diet in renal disease (MDRD) <30 mL/min) were excluded 5. The study complies with the Declaration of Helsinki and the protocol was approved by the local ethical committees and conducted accordingly.…”

Significance and Determinants of Cardiac Troponin I in Patients With Obstructive Hypertrophic Cardiomyopathy

“…8e10 LVMI was reported to be positively correlated with serum cTnI and cTnT and independently associated with increasing and elevated hs-cTnT concentrations. 6,11 Similarly, MWT and LVMI were significantly associated with both elevated cTnI and serum cTnI levels in our patients on univariate analysis. Furthermore, multivariate analysis showed that LVMI, but not MWT, was independently related to increasing and elevated cTnI levels.…”

“…The absence of hypertension was independently associated with both elevated cTnI and increasing serum cTnI levels in this study. On the contrary, Cramer et al 6 showed that the presence of hypertension was independently related to increasing hs-cTnT concentrations in 62 patients with HC. Potential mechanisms for this inconsistency are unclear, and we speculate that this phenomenon may be cohort specific.…”

High-sensitive troponin-T in adult congenital heart disease

“…With the recent introduction of highsensitive assays [4], smaller amounts of cardiomyocyte damage became detectable in various other cardiac conditions, including hypertension [5], hypertrophic cardiomyopathy [6], acute and chronic heart failure [7]. High-sensitive troponin-T (hs-TnT) improves risk stratification and is associated with adverse outcome in various cardiac diseases [8,9].…”