Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosis.

Further evidence of space-time clustering of Burkitt's lymphoma patients in the West Nile District of Uganda.

“…It is now clear, however, that infection with EBV is both world-wide and very common-in particular, it appears fairly certain to be the cause of infectious mononucleosis (Henle et al, 1968). Antibody levels to EBV have also been shown to be very similar in the Kigezi highlands of south-western Uganda, where no cases of Burkitt's lymphoma occur (Burkitt and Wright, 1966), and elsewhere in Uganda (Henle, G. and Henle, W., unpublished observations on serum supplied by the East African Virus Research Institute and related workers).…”

Epstein-Barr virus–associated lymphoproliferative disorders

“…Subsequent studies have proven that it is the causative agent in most cases of infectious mononucleosis [2]. Currently, it is estimated that more than 90% of the adult population worldwide are infected by the virus [3].…”

Hematologic differences in heterophile‐positive and heterophile‐negative infectious mononucleosis

“…Although the association of HA with IM was first demonstrated in 1932 [4], it was not until 1968 that EBV was shown to be the causative agent of the disease [5]. Since that time, rapid tests for the detection of HA in patients with IM have been shown to be highly specific for EBV infection [6].…”