Relation between migraine pattern and white matter hyperintensities in brain magnetic resonance imaging

Negm, Mohamed; Housseini, Ahmed M.; Abdelfatah, Mohamed M.; Asran, Alshimaa

doi:10.1186/s41983-018-0027-x

Cited by 28 publications

(50 citation statements)

References 25 publications

(61 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, the incidence of WMH in different migraine subtypes was 38.7-44.4% that complies with the middle position within the previously reported values between 29% and 73% [4][5][6][7][8] . The incidence of WMH was non-signi cantly higher in migraine with aura patients (44.4%), similarly to the results of other studies 5,6,9,10 . No signi cant differences in the incidence of WMH, its distribution across cerebral lobes and size of lesion between groups were found.…”

Section: Discussionsupporting

confidence: 90%

“…However, recent epidemiological studies have established that in 29-73% of migraine cases, T2 and FLAIR MRI scans reveal white matter hyperintensities (WMH) [4][5][6][7][8] . Most studies demonstrated WMH predominate in migraine with aura 5,6,9,10 and in chronic migraine 11,12 . The high incidence of WMH became one of the reasons to consider migraine as a risk factor for their development 9,11,[13][14][15][16] and highlighted the problem of the diagnostic and prognostic value of WMH in different types of migraine.…”

Section: Introductionmentioning

confidence: 99%

“…Several studies demonstrated the association between the WMH burden and the frequency of pain attacks 13,14,18 , duration of disorder 11,19 , its progression over time 6,16,20 , the risk of ischaemic stroke 21,22 and CI 23 , while other studies did not establish any relationship between WMH and severity or duration of migraine 4,[24][25][26] , risk of stroke and other vascular events 11,24 , CI 9,16,27,28 , and progression of WMH over time 29 . WMH in patients with different types of migraine are predominantly located within the frontal and parietal lobes 9,12,13,18,26,[30][31][32] , in deep and periventricular 6,8,10,13,26 , and sometimes juxtacortical white matter 20,31,32 , with sizes varying from small single to con uent larger lesions 20,[30][31][32] . WMH may be found along with asymptomatic small cerebral infarctions, mainly in the vertebrobasilar system 5,13,18,…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

White Matter Hyperintensity in Different Migraine Subtypes

Dobrynina¹,

Suslina²,

Губанова

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: The diagnostic value of white matter hyperintensities (WMH) in different types of migraine are unknown. Objective: To evaluate the WMH pattern of different subtypes in migraine patients with no vascular risk factors.Methods: 92 migraine patients (73 females, mean age 34.6±8.9; 61 episodic migraine, 31 chronic migraine, 36 migraine with aura, 56 migraine without aura) without vascular risk factors underwent brain MRI (3T). We also included a matched healthy control group with no migraine (n=24).Results: The prevalence of WMH in different types of migraine was similar and ranged from 38.7% to 44.4%; the control group showed no WMH at all. Lesions were located within frontal, parietal and temporal lobes (in order of decreasing incidence) in juxtacortical and/or deep white matter. WMH appeared as round or slightly elongated foci with a median size of 2.5 mm [1.5; 3]. Total number, size and prevalence of WMH by lobes and white matter regions were similar between groups, and no interaction with age or sex was found. The number of lesions within the frontal lobe juxtacortical white matter correlated with the age of patients (r= 0.331, p=0.001) and the duration since migraine onset (r=0.264, p=0.012). Conclusion: Patients with different migraine subtypes and without vascular risk factors are characterized by a similar pattern of WMH in the absence of subclinical infarctions or microbleedings. Therefore, WMH have no relevant prognostic value regarding the course of migraine and vascular complications. WMH pattern may be used to differentiate migraine as a primary disorder and other disorders with migraine-like headache and WMH.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

White Matter Hyperintensity in Different Migraine Subtypes

Dobrynina¹,

Suslina²,

Губанова

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Some studies reported a higher incidence of white matter hyperintensities in patients with migraine with aura compared to migraine without aura patients, while other studies reported a higher incidence of white matter hyperintensities in patients with migraine without aura when compared to migraine with aura patients. 15,[23][24][25][26][27] There are also studies that found no significant differences between both entities with regard to white-matter hyperintensitiesrelated variables. [28][29][30] In our study, there was no statistically significant white matter hyperintensities between patients with migraine aura and without aura.…”

Section: Discussionmentioning

confidence: 99%

White Matter Hyperintensities in Patients with Sporadic Hemiplegic Migraine

Nagarajan

Bollu

Sivaraman

et al. 2019

Journal of Neuroimaging

View full text Add to dashboard Cite

To identify the differences in overall occurrence, location, and disease burden of white matter hyperintensities (WMH) in patients with sporadic hemiplegic migraine (SHM) and patients with migraine headaches. METHODS: We included patients who met diagnostic criteria proposed by the third International Classification of Headache Disorders (ICHD-3) for SHM and migraine headache. WMHs were identified using T2 fluid-attenuated inversion recovery axial sequence and classified based upon the location. The disease burden was assessed using Scheltens visual rating scale. RESULTS: Fifty patients met the diagnostic criteria for SHM and 100 patients for migraine headache. Patients in the study group were similar to the control group in terms of age (47.7 ± 12.2 years vs. 48.17 ± 9.7 years; P = .814) and gender (M: F; 14:36 vs. M: F 25:75; P = .693). WMH were found in 28 (56%) patients with SHM and 44 (44%) in patients with migraine headache. The proportion of patients with WMH was not different between the two groups (P = .166). On univariate analysis, the proportion of patients with WMH in parietal, occipital, and infratentorial regions was higher in patients with SHM. White matter burden determined by visual rating scale and proportion of patients with lesions ࣙ5 mm in diameter was also significantly higher in patients with SHM. On multivariate analysis, the WMH occurrence in the parietal lobe (P = .043) was found to be significantly higher in SHM. CONCLUSIONS: The WMH occurrence in patients with SHM is significantly more in the parietal lobe when compared to those with migraine headaches. WMH burden was also higher in patients with SHM, and larger white matter lesions occurred more frequently in these patients with SHM (compared to ordinary migraineurs).

show abstract

“…Negm and co-workers [107] have found WM hyperintensities in 43.1% of migraine patients, and this phenomenon is more profound in patients suffering from migraine with aura.…”

Section: Migraine Attacks the Brainmentioning

confidence: 91%

Sensory guided associative learning in pediatric migraine without aura

Giricz

View full text Add to dashboard Cite

Relation between migraine pattern and white matter hyperintensities in brain magnetic resonance imaging

Cited by 28 publications

References 25 publications

White Matter Hyperintensity in Different Migraine Subtypes

White Matter Hyperintensity in Different Migraine Subtypes

White Matter Hyperintensities in Patients with Sporadic Hemiplegic Migraine

Sensory guided associative learning in pediatric migraine without aura

Contact Info

Product

Resources

About