Relation between heart rate and pulse transit time during paced respiration

Drinnan, Michael; Allen, John; Murray, Alan

doi:10.1088/0967-3334/22/3/301

Cited by 134 publications

(99 citation statements)

References 20 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Heart rate (HR) represents the cardiac cycle and determines the heart's preload and the cardiac output (CO), which positively impact BP as the pressure on the arterial walls. HR is proportional to the volume of blood ejected [115,116]. HR and BP are also regulated by the autonomic nervous system which has been found to be inversely related, depending on the baroreflex activity [117].…”

Section: Discussionmentioning

confidence: 99%

Cuff-Less and Continuous Blood Pressure Monitoring: A Methodological Review

et al. 2017

View full text Add to dashboard Cite

Blood pressure (BP) is one of the most important monitoring parameters in clinical medicine. For years, the cuff-based sphygmomanometer and the arterial invasive line have been the gold standards for care professionals to assess BP. During the past few decades, the wide spread of the oscillometry-based BP arm or wrist cuffs have made home-based BP assessment more convenient and accessible. However, the discontinuous nature, the inability to interface with mobile applications, the relative inaccuracy with movement, and the need for calibration have rendered those BP oscillometry devices inadequate for next-generation healthcare infrastructure where integration and continuous data acquisition and communication are required. Recently, the indirect approach to obtain BP values has been intensively investigated, where BP is mathematically derived through the "Time Delay" in propagation of pressure waves in the vascular system. This holds promise for the realization of cuffless and continuous BP monitoring systems, for both patients and healthy populations in both inpatient and outpatient settings. This review highlights recent efforts in developing these next-generation blood pressure monitoring devices and compares various mathematical models. The unmet challenges and further developments that are crucial to develop "Time Delay"-based BP devices are also discussed.

show abstract

Section: Discussionmentioning

confidence: 99%

Cuff-Less and Continuous Blood Pressure Monitoring: A Methodological Review

et al. 2017

View full text Add to dashboard Cite

show abstract

“…10 Data in humans regarding the relation between aortic PWV and LV myocardial shortening are limited, however. In 15 normal healthy subjects, Drinnan et al 28 found that changes in pulse transit time, from which PWV is calculated, follow changes in heart rate, thus suggesting indirectly that PWV may be influenced by myocardial function. Nürnberger et al 9 have shown that aortic PWV had an inverse relation with LV ejection time in young healthy men.…”

Section: Schillaci Et Al Aortic Pulse Wave Velocity and The Heartmentioning

confidence: 99%

Age-Specific Relationship of Aortic Pulse Wave Velocity With Left Ventricular Geometry and Function in Hypertension

et al. 2007

View full text Add to dashboard Cite

Abstract-Aortic pulse wave velocity (PWV), generally considered an intrinsic marker of arterial stiffness, might depend in part on the velocity of myocardial fiber shortening, but the relation between PWV and myocardial function in humans has been understudied. A total of 237 untreated hypertensive subjects over a wide age range (18 to 88 years) underwent aortic PWV determination and echocardiography, from which the mean velocity of circumferential fiber shortening was calculated as a measure of the velocity of myocardial shortening, and relative wall thickness was taken as a measure of left ventricular concentric remodeling. Patients were divided in 3 age groups (Ͻ40 years, 40 to 59 years, and Ն60 years).In the young, aortic PWV was directly associated with heart rate-corrected velocity of circumferential fiber shortening (rϭ0. arge-artery stiffness is increasingly recognized as an early marker of future cardiovascular disease and mortality in different clinical settings, including essential hypertension, the general population, and chronic kidney disease. [1][2][3][4][5] The availability of applanation tonometry-based techniques for measuring pulse wave velocity (PWV) provided a simple, accurate, noninvasive means for the determination of large-artery stiffness. Aortic PWV is considered an intrinsic measure of arterial stiffness on the basis of the Moens-Korteweg equation 6 and, as a measure of aortic impedance and an integrated marker of the pulsatile component of left ventricular (LV) afterload, has been linked to a prognostically adverse cardiac phenotype, including concentric remodeling and depressed LV systolic function. 7,8 On the other hand, the pulse wave is generated by the contracting heart, and it has been hypothesized that aortic PWV might be determined in part by enhanced myocardial performance, at least in young subjects. Indeed, aortic PWV has been associated with a shortened LV ejection time in young healthy men. 9 Because the initial speed of the pressure wave is mainly determined by the velocity of myocardial shortening, 10 and LV ejection time is correlated with shortening velocity, 11 these data can be taken as an indirect suggestion that myocardial function might influence the characteristics of the pulse pressure wave in humans.However, the relation between aortic PWV and a direct measure of ventricular systolic performance has not been defined clearly. We explored the link between aortic PWV and LV geometry and function, as well as the influence of age on this relationship, in a large, untreated series of uncomplicated subjects with essential hypertension. MethodsIn our study, we recruited 237 subjects with essential hypertension who had been consecutively referred to our hypertension outpatient clinic by their general practitioners for baseline, off-treatment

show abstract

“…To keep respiration a narrow-band signal to eliminate respiratory confounds (e.g., power spectral analysis [12,26]), paced breathing (PB) procedure is commonly performed [8,21,29]. It has been demonstrated that PB procedure can lead to increased amplitude oscillations in both HR and BP when breathing rate becomes lower [36,37].…”

Section: Introductionmentioning

confidence: 99%

Effects of slow and regular breathing exercise on cardiopulmonary coupling and blood pressure

Zhang

Wang²,

Wu³

et al. 2016

Med Biol Eng Comput

View full text Add to dashboard Cite

Meanwhile, BP was reduced significantly by the SPB procedure (SBP: from 122.0 ± 13.4 to 114.2 ± 14.9 mmHg, p < 0.001, DBP: from 82.2 ± 8.6 to 77.0 ± 9.8 mmHg, p < 0.001, PTT: from 172.8 ± 20.1 to 176.8 ± 19.2 ms, p < 0.001). Our results demonstrate that the SPB procedure can reduce BP and lengthen PTT significantly. Compared with amplitude dynamics, phase dynamics is a different marker for CPC analysis in reflecting cardiorespiratory coherence during slow breathing exercise. Our study provides a methodology to practice slow breathing exercise, including the setting of target breathing rate, change of CPC and the importance of regular breathing. The applications and usability of the study results have also been discussed.

show abstract

Relation between heart rate and pulse transit time during paced respiration

Cited by 134 publications

References 20 publications

Cuff-Less and Continuous Blood Pressure Monitoring: A Methodological Review

Cuff-Less and Continuous Blood Pressure Monitoring: A Methodological Review

Age-Specific Relationship of Aortic Pulse Wave Velocity With Left Ventricular Geometry and Function in Hypertension

Effects of slow and regular breathing exercise on cardiopulmonary coupling and blood pressure

Contact Info

Product

Resources

About