“…1, Marked to diffuse loss of fat from the lower extremities, associated in some with small focal areas of loss on the arms and Iipoatrophy of buttock in one (16,(18)(19)(20) 2, Small to moderate-sized, multifocal, localized lipoatrophic areas that did not extend over the whole extremity, involving thigh, lower leg, and occasionally arms (18,20) 3, Localized atrophy in a semicircular pattem around the ankles (21) 4, Localized atrophic or depressed areas on the face (cheeks, bridge of nose, preauricuiar area), upper arms, shoulders, and neck after LE or connective tissue panniculitis (13,15; pt, no, 2) 5, Depressed or pitted areas in scattered distribution after liquefaction of fat and/or abscess formation (7,14) Lipoatrophy was noted in only one of the seven children with fatal panniculitis (9) and followed the second pattem. Suppuration or ulceration of lesions was noted in seven patients (4,5,7,11,12,14; pt.…”