Relapsed Esophageal Web in a Patient with Plummer-Vinson Syndrome

Won, Kang Yeon; Ju, Il Nam; Moon, Hyung Il; Choi, Woo Hyung; Jung, Sung Min; Choi, Hye Jin; Oh, Se Jin; Kang, Hyeon Jeong; Lee, Dong Jae; Kim, Kyung Hyun; Jung, Gu Sung; Lee, Seung Woo

doi:10.7704/kjhugr.2014.14.2.117

Cited by 3 publications

(6 citation statements)

References 9 publications

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“…10,13 Another caution is that iron supplementation needs to be maintained. As in the present case, Won et al 8 reported dysphagia recurrence because the IDA was not corrected after endoscopic balloon dilatation. Previous studies have reported that upper gastrointestinal tract squamous cell carcinoma occurs in about 3~16% of patients with PVS.…”

Section: 10supporting

confidence: 51%

“…Treatment of PVS primarily involves the non-invasive administration of iron; however, if the symptoms do not improve after iron intake or if iron supplements cannot be administered, invasive methods (e.g., endoscopic swelling or balloon dilatation, electrocautery, and, rarely, surgery) may be considered. 1,3,8,9 Importantly, prior to beginning iron supplements to correct the IDA, the cause of the anemia must be determined and appropriately treated. Iron deficiency is most often caused by excessive menstruation or chronic blood loss from the gastrointestinal tract including peptic ulcers, hemorrhoids, vascular abnormalities, and malignant diseases.…”

Section: 10mentioning

confidence: 99%

“…1,2 The prog-nosis is good, and recurrence is rare when iron supplementation is continued. 8 A middle-aged woman visited our center because of dysphagia, and was diagnosed with a simple esophageal membrane, despite endoscopic evidence of an upper esophageal web and blood tests that revealed IDA. She underwent digestive tract dilatation and received no further follow-up.…”

Section: Introductionmentioning

confidence: 99%

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Accidentally Confirmed Relapse of Plummer-Vinson Syndrome during Esophageal Foreign Body Evaluation

Kang

Kim

Seo

2022

Korean J Helicobacter Up Gastrointest Res

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Plummer-Vinson syndrome (PVS) is a complex condition characterized by a classic triad of dysphagia, iron deficiency anemia (IDA), and an upper esophageal web. Dysphagia represents the most important symptom of PVS and is usually observed with solid food. Therapeutic options for dysphagia include iron supplementation and/or endoscopic balloon dilation based on symptom severity. PVS can be treated easily and regular iron replacement therapy can prevent disease progression. We describe a 63-year-old woman diagnosed with a simple esophageal web, who underwent esophageal dilation 13 years prior to presentation. However, she revisited our center because of dysphagia secondary to an esophageal foreign body, and endoscopy revealed esophageal web relapse. Investigations revealed IDA, and the patient was eventually diagnosed as PVS. She underwent successful endoscopic dilation and denied recurrent dysphagia after continuous intake of iron tablets. We recommend continuous management of IDA, as well as endoscopic dilation and a multidisciplinary therapeutic approach to ensure favorable prognosis in PVS patients.

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Section: 10supporting

confidence: 51%

Section: 10mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Accidentally Confirmed Relapse of Plummer-Vinson Syndrome during Esophageal Foreign Body Evaluation

Kang

Kim

Seo

2022

Korean J Helicobacter Up Gastrointest Res

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“…The frequency of reported cases has decreased which may possibly be due to the overall improvement in nutrition and health care [2]. The syndrome occurs more commonly in middle-aged women, approximately 9 times more frequently than men [2,3]. Although the exact etiopathogenesis of this entity is unclear, several hypotheses have been made, the most popular of which is based on iron-dependent oxidative enzyme deficiency [2,4].…”

Section: Discussionmentioning

confidence: 99%

“…Correction of anemia via oral or intravenous route may be sufficient to eradicate the web and resolve dysphagia in patients who are not considerably obstructed. Patients who have failed conservative hematinic management and others who are inherently obstructed like the index case will require endoscopic therapeutic intervention [3]. Plummer-Vinson syndrome is considered a premalignant condition and as such, long-term follow-up of the post-cricoid region is mandatory [1,3,9].…”

Section: Discussionmentioning

confidence: 99%

Plummer–Vinson syndrome: A rare case of dysphagia in a middle aged female

Figaro¹,

Figaro²,

Solomon³

et al. 2022

J Case Rep Images Med

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A 42-year-old female presented to the Otolaryngology Department with a two year history of progressive dysphagia to solids. She did not have any comorbidities yet complained of fatigue and shortness of breath on exertion. When questioned about her menstrual cycle, the patient was unaware that she was having menorrhagia for several years. Her physical examination was normal with the exception of her skin pallor and platynychia (Figure 1). Hematological investigation revealed a hemoglobin level of 6.5 g/dL, hematocrit of 24%, mean corpuscular volume of 58.5 fL, a red cell distribution width of 19.1%, and a serum ferritin level of 9 ng/mL. Barium esophagogram demonstrated an esophageal web within the proximal esophagus at the level of the C6 vertebral body (Figure 2). A diagnosis of Plummer-Vinson syndrome was made and the patient was referred to gastroenterologist for therapeutic intervention.

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Gastric Cancer Accompanying Plummer-Vinson Syndrome

Im¹,

Kim²,

Park³

et al. 2020

Korean J Helicobacter Up Gastrointest Res

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Plummer-Vinson syndrome (PVS), also called sideropenic dysphagia or Paterson-Kelly syndrome, is a condition characterized by a triad of chronic iron-deficiency anemia, esophageal webs, and dysphagia. This syndrome is considered as a precancerous condition due to the occurrence of squamous cell carcinoma in the hypopharynx, upper esophagus and oral cavity. Although exact data on the prevalence of the syndrome are not evidently available, physicians need to recognize this rare syndrome. Most of the patients are elderly Caucasian women aged 40 to 70 years, but cases in children, adolescents, or men have also been described. At present, the prevalence of PVS is decreasing due to improvement in nutritional habits and intake of iron supplements. Therefore, the syndrome accompanied with gastric cancer is even more uncommon. We report a case of a 61-year-old woman with PVS who was diagnosed with gastric cancer and improved after treatment.

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Relapsed Esophageal Web in a Patient with Plummer-Vinson Syndrome

Cited by 3 publications

References 9 publications

Accidentally Confirmed Relapse of Plummer-Vinson Syndrome during Esophageal Foreign Body Evaluation

Accidentally Confirmed Relapse of Plummer-Vinson Syndrome during Esophageal Foreign Body Evaluation

Plummer–Vinson syndrome: A rare case of dysphagia in a middle aged female

Gastric Cancer Accompanying Plummer-Vinson Syndrome

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