Relación del test de control del asma (ACT) con la función pulmonar, niveles de óxido nítrico exhalado y grados de control según la Iniciativa Global para el Asma (GINA)

Álvarez-Gutiérrez, Francisco Javier; Gallardo, J.F. Medina; Pérez-Navarro, Pablo; Martín-Villasclaras, Juan José; Etchegoren, Bernardo Martin; Romero-Romero, Beatriz; Praena-Fernández, Juan Manuel

doi:10.1016/j.arbres.2010.04.003

Cited by 28 publications

(11 citation statements)

References 18 publications

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“…Similar discrepancies have been observed in different studies where ACQ or ACT questionnaires have been used as a predictor of GINA-defined asthma control [8,24] . Thus, the study by Alvarez-Gutiérrez et al [24] found different cut-off points for ACT than previously described (≤ 18 for uncontrolled asthma), suggesting that a more complete assessment would require monitoring operating parameters and FeNO.…”

Section: Discussionsupporting

confidence: 83%

“…Thus, the study by Alvarez-Gutiérrez et al [24] found different cut-off points for ACT than previously described (≤ 18 for uncontrolled asthma), suggesting that a more complete assessment would require monitoring operating parameters and FeNO. In the study published by Thomas et al [8], a multinational cross-sectional survey conducted in Primary Care, Pulmonology and Allergology settings from France, Germany, Italy, Spain and US, and in Primary Care and Pulmonology departments in UK, a total of 2,949 patients filled out the ACT and physician’s case report forms with questions related to GINA classification without spirometry.…”

Section: Discussionmentioning

confidence: 89%

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Measurement of asthma control according to global initiative for asthma guidelines: a comparison with the asthma control questionnaire

et al. 2012

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IntroductionAsthma Control Questionnaire (ACQ) is a validated tool to measure asthma control. Cut-off points that best discriminate “well-controlled” or “not well-controlled” asthma have been suggested from the analysis of a large randomized clinical trial but they may not be adequate for daily clinical practice.AimsTo establish cut-off points of the ACQ that best discriminate the level of control according to Global Initiative for Asthma (GINA) 2006 guidelines in patients with asthma managed at Allergology and Pulmonology Departments as well as Primary Care Centers in Spain.Patients and methodsAn epidemiological descriptive study, with prospective data collection. Asthma control following GINA-2006 classification and 7-item ACQ was assessed. The study population was split in two parts: 2/3 for finding the cut-off points (development population) and 1/3 for validating the results (validation population).ResultsA total of 1,363 stable asthmatic patients were included (mean age 38 ± 14 years, 60.3% women; 69.1% non-smokers). Patient classification according to GINA-defined asthma control was: controlled 13.6%, partially controlled 34.2%, and uncontrolled 52.3%. The ACQ cut-off points that better agreed with GINA-defined asthma control categories were calculated using receiver operating curves (ROC). The analysis showed that ACQ < 0.5 was the optimal cut-off point for “controlled asthma” (sensitivity 74.1%, specificity 77.5%) and 1.00 for “uncontrolled asthma” (sensitivity 73%, specificity 88.2%). Kappa index between GINA categories and ACQ was 0.62 (p < 0.001).ConclusionThe ACQ cut-off points associated with GINA-defined asthma control in a real-life setting were <0.5 for controlled asthma and ≥1 for uncontrolled asthma.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 89%

Measurement of asthma control according to global initiative for asthma guidelines: a comparison with the asthma control questionnaire

et al. 2012

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“…The ACT is easily and quickly completed by patients and can serve as a useful tool in everyday practice to guide adjustments in asthma therapy (9). The GINA guideline on the other hand is based on expert consensus and has not yet been validated in real world practice (10, 11). Thus, the ACT is a more suitable instrument for assessing control when patients are directly asked about their symptoms (3).…”

Section: Discussionmentioning

confidence: 99%

Assessing Control of Asthma in Jush, Jimma, South West Ethiopia

Zemedkun¹,

Woldemichael²,

Tefera³

2014

Ethiop J Health Sci

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BackgroundDespite international guidelines, asthma control is short of the goal in different parts of the world. The objective of this study was to assess control of asthma in patients older than 14 years at the Chest Clinic of Jimma University Specialized Hospital/JUSH, South West Ethiopia.MethodsA cross-sectional hospital-based study was conducted on 234 physician-diagnosed asthmatic patients attending the chest follow up clinic from June 01 to July 31, 2012. Asthma control was assessed using the GINA algorithm and the ACT questionnaire. Pulmonary function test was measured using a spirometer for 160 subjects. Data were cleared, entered and analyzed using SPSS version 16 and independent variables were assessed for association with the level of asthma control using bivariate and multinomial analyses.ResultsUsing the GINA based algorithm, 42 respondents (26.2%) were considered to have partly controlled asthma and the majority, 117 (76.1%), had uncontrolled asthma. Asthma was uncontrolled (ACT score <19) in 71.4% subjects and well-controlled (ACT score = 20–25) in 28.6%. Inhaled corticosteroids alone or in association with long-acting b-agonists, which are the prophylactic treatments recommended by GINA, were used by only 9 subjects (3.8%). Factors associated independently with asthma control were individual patient's age group, unscheduled visit, frequency of SABA use, type of treatment and perceived rate of asthma control.ConclusionAsthma control is unacceptably poor in Jimma, South West Ethiopia. This could be changed through improved appropriate treatment and frequent monitoring to achieve and maintain control.

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“…19–21 However, other studies carried out in Spain, Taiwan and Netherlands reported that higher C-ACT or ACT cut-points were more accurate in determining asthma control when compared to Global Initiative for Asthma (GINA) guidelines. 13, 14, 22 These studies suggested different perceptions of asthma symptoms in different ethnic populations and social settings may give insight into why a higher C-ACT/ACT cut-point is necessary for Mexican descent children in OC. Our results showed that in the Mexican descent children, the standard cut-point of C-ACT/ACT ≤ 19 had high specificities in predicting uncontrolled asthma, with very limited sensitivities (33% for C-ACT and 41% for ACT).…”

Section: Discussionmentioning

confidence: 97%

“…Numerous studies have previously shown poor correlations between asthma control tests and lung function measured by traditional spirometry 13, 20, 22, 25 . In the present study, spirometry measurements did not correlate well with C-ACT/ACT scores.…”

Section: Discussionmentioning

confidence: 99%

Cut points for Asthma Control Tests in Mexican children in Orange County, California

Shi

Tatavoosian

Aledia

et al. 2012

Annals of Allergy, Asthma & Immunology

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Relación del test de control del asma (ACT) con la función pulmonar, niveles de óxido nítrico exhalado y grados de control según la Iniciativa Global para el Asma (GINA)

Cited by 28 publications

References 18 publications

Measurement of asthma control according to global initiative for asthma guidelines: a comparison with the asthma control questionnaire

Measurement of asthma control according to global initiative for asthma guidelines: a comparison with the asthma control questionnaire

Assessing Control of Asthma in Jush, Jimma, South West Ethiopia

Cut points for Asthma Control Tests in Mexican children in Orange County, California

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