Rejuvenation: Brown-Sequard to Brinkley, Monkey Glands to Goat Glands

Doctor Sergei Abramovich Voronoff (Serge Voronoff) — the Сhampion for preserving youth and eternal life. At the origins of transplant endocrinology

“…Как нередко бывает, при появлении новых направлений в медицине, операций и лекарств появляются шарлатаны, стремящиеся извлечь из этого материальную выгоду. Например, «доктор» J. Brinkley [42], недоучившийся врач, купивший диплом в университете в Канзасе и занявшийся частной практикой. Он сразу понял перспективность борьбы со старением.…”

The ambit of periodontal reproductive endocrinology

“…Nevertheless, misinformation came even from well‐educated, well‐meaning physicians who ultimately provided their limited, somewhat biased and controversial findings to the public. In the 19th century, Charles‐Édouard Brown‐Séquard, an eminent French physician and physiologist, made and injected an elixir of animal testicular extracts, which he professed increased his physical strength and intellectual prowess, relieved his constipation and even lengthened the arc of his urine (13, 37). Earlier in the century, observations by renowned American physician William Potts Dewees, of women with an abnormally heavy and prolonged menstrual period, led to the conclusion that ‘women who were most obnoxious to menorrhagia are those who are too prodigal in the joys of wedlock’ (39).…”

Reproductive hormonal treatments for mood disorders in women

“…His description of the invigorating effects of testicular extracts resulted in a brief but widespread use of these compounds (as well as other interventions intended to increase the body's testicular or seminal fluid levels) in a variety of therapeutic settings. 12 - 14 In addition to extracts of both testes and ovaries, investigators experimented with extracts of the thyroid and adrenal glands in psychiatric patients. 10 This interest in thyroid and adrenal extracts enjoyed more enduring success with the recognition of their beneficial effects in the treatment of myxedema and Addison's disease, respectively.…”