The aim of most of the current studies in the field of educational psychology is focused on, apart from the aspects of learning and school success, the emotional and social experiences of adolescents, as well as on their perception of school. The aim of this research was to examine the predictive contribution of academic and social factors (social self-efficiency, perceived academic control, social integration and perceived teacher support) in explaining students' school satisfaction in early adolescence. The research comprised pertinent sample of 230 participants, 120 female and 110 male, from Valjevo, aged 14,52±1,38. The following measuring instruments were used: Perceived academic control scale (PAC), Selfefficiency questionnaire for children (SEQ-C), Learning climate questionnaire (LCQ) and The quality of school life (QSL), all of which showed satisfactory internal consistency. The obtained results of nonparametric Pearson correlation coefficient indicated the existence of statistically significant, low and moderate, positive correlation between scores on the scales and questionnaires PAC, SEQ-C, LCQ and QSL (p < 0.01). The results of hierarchical regression analysis suggest that academic and social variables explain 61% of total criterion variance, and individual statistically significant predictors of general school satisfaction are: teacher support, social integration, perceived academic control, social self-efficiency and school success. That revealed that preadolescents with higher scores on those variables also achieve higher scores on school success scale. In addition, this research considers practical and theoretical implication of the obtained results for creating encouraging school environment during the period of early adolescence. The obtained results on students' opinion on their skills can have practical implications and can be useful in diagnosing and planning academic and social determinants, which contribute positively to students' perception of general school satisfaction and relation between curricular and extracurricular activities in Serbia.